X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution
about
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanismCrystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coliCrystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapyPolyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteriaStructural basis for the efficient phosphorylation of AZT-MP (3'-azido-3'-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinaseStructure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase.A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.Coupling of NAD+ biosynthesis and nicotinamide ribosyl transport: characterization of NadR ribonucleotide kinase mutants of Haemophilus influenzaeOptimization of Structure Based Virtual Screening Protocols Against Thymidine Monophosphate Kinase Inhibitors as Antitubercular Agents.Protein targets for structure-based anti-Mycobacterium tuberculosis drug discovery.Nucleoside analogs and tuberculosis: new weapons against an old enemy.Sero-diagnosis of Active Mycobacterium tuberculosis Disease among HIV Co-infected Persons using Thymidylate Kinase based Antigen and Antibody Capture Enzyme Immuno-Assays.Immuno-diagnosis of Mycobacterium tuberculosis in sputum, and reduction of timelines for its positive cultures to within 3 h by pathogen-specific thymidylate kinase expression assays.5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis.Design of Thymidine Analogues Targeting Thymidilate Kinase of Mycobacterium tuberculosis.Development of new antituberculous agents based on new drug targets and structure-activity relationship.A novel viral thymidylate kinase with dual kinase activity.Indispensable residue for uridine binding in the uridine-cytidine kinase family.Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding.Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase.Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery.Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: fragment-based QSAR and QM/MM docking studies.Nucleoside analogues as inhibitors of thymidylate kinases: possible therapeutic applications.Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.
P2860
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P2860
X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@ast
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@en
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@nl
type
label
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@ast
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@en
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@nl
prefLabel
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@ast
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@en
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@nl
P2093
P356
P1476
X-ray structure of TMP kinase ...... with TMP at 1.95 A resolution
@en
P2093
A M Gilles
H Munier-Lehmann
I Li de la Sierra
P304
P356
10.1006/JMBI.2001.4843
P407
P577
2001-08-03T00:00:00Z