Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism
about
Structural basis for the efficient phosphorylation of AZT-MP (3'-azido-3'-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinaseOptimization of Structure Based Virtual Screening Protocols Against Thymidine Monophosphate Kinase Inhibitors as Antitubercular Agents.Protein targets for structure-based anti-Mycobacterium tuberculosis drug discovery.5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis.Stereocontrolled facile synthesis and biological evaluation of (3'S) and (3'R)-3'-amino (and Azido)-3'-deoxy pyranonucleosides.Design of Thymidine Analogues Targeting Thymidilate Kinase of Mycobacterium tuberculosis.Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding.Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase.Antioxidant Activity of a Series of Fluorinated Pyrano-nucleoside Analogues of N4-benzoyl Cytosine and N6-benzoyl Adenine.Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery.
P2860
Q27660369-10612E03-2DDF-4B0F-87A3-528289DF2A2AQ36088910-C26768AC-EF19-4E2A-84FE-6B05E64E087AQ37825826-082C1C3D-B472-476C-8D68-EFDE6CA09577Q38865447-FB611398-3868-4990-9304-6F60F8B4590AQ39304832-8D6D219F-B593-4E77-A903-64DDC0546478Q39672216-7FCA5E7F-1DA1-4F32-898B-894D949916BFQ41840329-EF143544-534E-4217-9836-09A526144A81Q42277625-3348CE41-FF6E-4163-B78B-B2A7B6F6338CQ46029710-B444D095-A845-418D-A11F-DC0DEBC224C3Q46173578-BEEC8E6E-31EF-4A77-BBA9-B627EF2E8CDB
P2860
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@ast
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@en
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@nl
type
label
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@ast
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@en
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@nl
prefLabel
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@ast
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@en
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@nl
P2860
P50
P356
P1476
Enzymatic and structural analy ...... phosphoryl transfer mechanism
@en
P2093
Mattheus Froeyen
Veerle Vanheusden
P2860
P304
P356
10.1074/JBC.M209630200
P407
P577
2003-02-14T00:00:00Z