Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding
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Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.Protein–Ligand Interactions: Thermodynamic Effects Associated with Increasing Nonpolar Surface AreaExtreme Entropy–Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 ProteaseProtein–ligand interactions: Probing the energetics of a putative cation–π interactionConformational determinants of phosphotyrosine peptides complexed with the Src SH2 domainStructural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.Relative Binding Enthalpies from Molecular Dynamics Simulations Using a Direct Method.Constraining binding hot spots: NMR and molecular dynamics simulations provide a structural explanation for enthalpy-entropy compensation in SH2-ligand bindingBinding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization.Probing the effect of conformational constraint on phosphorylated ligand binding to an SH2 domain using polarizable force field simulations.Detection of long-range concerted motions in protein by a distance covariance.Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain.Protein-Ligand Interactions: Thermodynamic Effects Associated with Increasing the Length of an Alkyl Chain.Natural Products and Their Mimics as Targets of Opportunity for Discovery.Evaluating the dynamics and electrostatic interactions of folded proteins in implicit solvents.Rapid synthesis of cyclopropane-dipeptide analogues.Increased Conformational Flexibility of a Macrocycle-Receptor Complex Contributes to Reduced Dissociation Rates.Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers.Synthesis of the Src SH2 domain and its application in bioassays for mirror-image screeningLinear starch and hexanoic acid complexation evaluated by isothermal titration calorimetry
P2860
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P2860
Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Calorimetric and structural st ...... tors of Src SH2 domain binding
@ast
Calorimetric and structural st ...... tors of Src SH2 domain binding
@en
Calorimetric and structural st ...... tors of Src SH2 domain binding
@nl
type
label
Calorimetric and structural st ...... tors of Src SH2 domain binding
@ast
Calorimetric and structural st ...... tors of Src SH2 domain binding
@en
Calorimetric and structural st ...... tors of Src SH2 domain binding
@nl
prefLabel
Calorimetric and structural st ...... tors of Src SH2 domain binding
@ast
Calorimetric and structural st ...... tors of Src SH2 domain binding
@en
Calorimetric and structural st ...... tors of Src SH2 domain binding
@nl
P2093
P356
P1476
Calorimetric and structural st ...... tors of Src SH2 domain binding
@en
P2093
James P Davidson
Olga Lubman
Stephen F Martin
Thierry Rose
P304
P356
10.1021/JA011746F
P407
P577
2002-01-16T00:00:00Z