Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase
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Structural Characterization of the Molecular Events during a Slow Substrate–Product Transition in Orotidine 5′-Monophosphate DecarboxylaseAtomic Resolution Structure of the Orotidine 5'-Monophosphate Decarboxylase Product Complex Combined with Surface Plasmon Resonance Analysis: IMPLICATIONS FOR THE CATALYTIC MECHANISMSubstrate Distortion Contributes to the Catalysis of Orotidine 5′-Monophosphate DecarboxylaseAccelerated hydrolysis of α-halo and α-cyano pyridinium relative to uracil derivatives: a model for ODCase-catalyzed hydrolysis of 6-cyanoUMPPolarization in the structures of uracil and thiouracils: Implication for binding with orotidine 5'-monophosphate decarboxylaseHydrolysis of α-chloro-substituted 2- and 4-pyridones: rate enhancement by zwitterionic structure.Mechanisms and free energies of enzymatic reactions.Bayesian reconstruction of P(r) directly from two-dimensional detector images via a Markov chain Monte Carlo methodIndiscriminate binding by orotidine 5'-phosphate decarboxylase of uridine 5'-phosphate derivatives with bulky anionic c6 substituents.Stabilities of Uracil and Pyridone-Based Carbanions: A Systematic Study in the Gas Phase and Solution and Implications for the Mechanism of Orotidine-5'-Monophosphate Decarboxylase.Specificity in transition state binding: the Pauling model revisited.Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.Design of inhibitors of ODCase.Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.
P2860
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P2860
Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase
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2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@ast
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@en
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@nl
type
label
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@ast
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@en
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@nl
prefLabel
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@ast
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@en
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@nl
P2860
P356
P1476
Crystal structures of inhibito ...... 5'-monophosphate decarboxylase
@en
P2093
P2860
P304
P356
10.1074/JBC.M202362200
P407
P50
P577
2002-08-02T00:00:00Z