about
Anabaena circadian clock proteins KaiA and KaiB reveal a potential common binding site to their partner KaiCHydrophobic Gating of Ion Permeation in Magnesium Channel CorAMapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallographyCrystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylaseCrystal structure of Methanobacterium thermoautotrophicum conserved protein MTH1020 reveals an NTN-hydrolase foldAn extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibitionAtomic model of human Rcd-1 reveals anarmadillo-like-repeat protein with in vitro nucleic acid binding propertiesMutational, structural, and kinetic studies of the ATP-binding site of Methanobacterium thermoautotrophicum nicotinamide mononucleotide adenylyltransferaseA potent, covalent inhibitor of orotidine 5'-monophosphate decarboxylase with antimalarial activityTwo mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidaseStructure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylaseMechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinolCrystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirusStructural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding siteStructural Characterization of the Molecular Events during a Slow Substrate–Product Transition in Orotidine 5′-Monophosphate DecarboxylaseStructure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agentsCrystallographic Definition of the Epitope Promiscuity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5: Vaccine Design ImplicationsStructural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylaseCrystal structure of a truncated urease accessory protein UreF from Helicobacter pyloriPrion disease susceptibility is affected by -structure folding propensity and local side-chain interactions in PrPCrystal structures of urate bound form of xanthine oxidoreductase: substrate orientation and structure of the key reaction intermediateLinkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylaseCrystal structure of metarhodopsin IINovel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate DecarboxylaseMapping the Reaction Coordinates of Enzymatic DefluorinationCrystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspPStructural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitopeProtein Conformational Gating of Enzymatic Activity in Xanthine OxidoreductaseAtomic Resolution Structure of the Orotidine 5'-Monophosphate Decarboxylase Product Complex Combined with Surface Plasmon Resonance Analysis: IMPLICATIONS FOR THE CATALYTIC MECHANISMN-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion ProteinsSubstrate Distortion Contributes to the Catalysis of Orotidine 5′-Monophosphate DecarboxylaseStructure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 EpitopeNovel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twistAtomic structure of the actin:DNase I complexOpsin, a structural model for olfactory receptors?Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductaseCharacterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus
P50
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P50
description
hulumtues
@sq
onderzoeker
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հետազոտող
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name
Emil F Pai
@fr
Emil F. Pai
@en
Emil F. Pai
@es
Emil F. Pai
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Emil F. Pai
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type
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Emil F Pai
@fr
Emil F. Pai
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Emil F. Pai
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Emil F. Pai
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Emil F. Pai
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Emil F Pai
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prefLabel
Emil F Pai
@fr
Emil F. Pai
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Emil F. Pai
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Emil F. Pai
@nl
Emil F. Pai
@sl
P106
P1153
7005382221
P21
P31
P4012
P496
0000-0002-1162-7242