The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs
about
The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sitesTom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrinCrystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5Interactions of GGA3 with the ubiquitin sorting machineryStructural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent SortingLsb5p interacts with actin regulators Sla1p and Las17p, ubiquitin and Arf3p to couple actin dynamics to membrane trafficking processesTollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomesUbiquitin-binding domainsWAVE regulatory complex activation by cooperating GTPases Arf and Rac1GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins.The GAT domains of clathrin-associated GGA proteins have two ubiquitin binding motifsEpidermal growth factor-dependent phosphorylation of the GGA3 adaptor protein regulates its recruitment to membranes.Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling.The role of cargo proteins in GGA recruitment.PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signalCOG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integritySmap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia.Structure of Golgi transport proteins.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.The acidic cluster of the CK2 site of the cation-dependent mannose 6-phosphate receptor (CD-MPR) but not its phosphorylation is required for GGA1 and AP-1 binding.Multiple phosphorylation events regulate the subcellular localization of GGA1.
P2860
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P2860
The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
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2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
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2003年论文
@wuu
name
The structure of the GGA1-GAT ...... d membrane association of GGAs
@ast
The structure of the GGA1-GAT ...... d membrane association of GGAs
@en
The structure of the GGA1-GAT ...... d membrane association of GGAs
@nl
type
label
The structure of the GGA1-GAT ...... d membrane association of GGAs
@ast
The structure of the GGA1-GAT ...... d membrane association of GGAs
@en
The structure of the GGA1-GAT ...... d membrane association of GGAs
@nl
prefLabel
The structure of the GGA1-GAT ...... d membrane association of GGAs
@ast
The structure of the GGA1-GAT ...... d membrane association of GGAs
@en
The structure of the GGA1-GAT ...... d membrane association of GGAs
@nl
P1433
P1476
The structure of the GGA1-GAT ...... d membrane association of GGAs
@en
P2093
David J Owen
Peter J Watson
P304
P356
10.1016/S1534-5807(03)00037-6
P407
P577
2003-03-01T00:00:00Z