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WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

http://www.wikidata.org/entity/Q30503973

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Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes Rab1 recruits WHAMM during membrane remodeling but limits actin nucleation.Arf1 and Arf6 promote ventral actin structures formed by acute activation of protein kinase C and Src The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth Allosteric N-WASP activation by an inter-SH3 domain linker in Nck WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.The Drosophila Arf1 homologue Arf79F is essential for lamellipodium formation.Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein.Homer3 regulates the establishment of neutrophil polarity WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion.Myoblast fusion: lessons from flies and mice.Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments.Brefeldin A-inhibited ADP-ribosylation factor activator BIG2 regulates cell migration via integrin β1 cycling and actin remodeling.Cellular functions of WASP family proteins at a glance.ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology.Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases ARP2/3-dependent growth in the plant kingdom: SCARs for life.Arf6 coordinates actin assembly through the WAVE complex, a mechanism usurped by Salmonella to invade host cells.CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.In vitro studies of actin filament and network dynamics.Structural features and interfacial properties of WH2, β-thymosin domains and other intrinsically disordered domains in the regulation of actin cytoskeleton dynamics.Self-organization of protrusions and polarity during eukaryotic chemotaxis.Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.Phagocytosis: receptors, signal integration, and the cytoskeleton.Biochemical reconstitution of the WAVE regulatory complex.Arf GTPase interplay with Rho GTPases in regulation of the actin cytoskeleton.Swiss Army Pathogen: The Salmonella Entry Toolkit.MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells.Inhibition of WAVE Regulatory Complex Activation by a Bacterial Virulence Effector Counteracts Pathogen Phagocytosis The Arf GTPase-activating protein family is exploited by Salmonella enterica serovar Typhimurium to invade nonphagocytic host cells.Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion.ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis.A module for Rac temporal signal integration revealed with optogenetics.The WAVE Regulatory Complex and Branched F-Actin Counterbalance Contractile Force to Control Cell Shape and Packing in the Drosophila Eye.Molecular Control of Actin Dynamics In Vivo: Insights from Drosophila.

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P2860

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

http://www.wikidata.org/entity/Q30503973

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

@ast

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

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type

label

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

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WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

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prefLabel

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

@ast

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

@en

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Proceedings of the National Academy of Sciences of the United States of America

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WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

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P2093

Daniel Humphreys

http://www.w3.org/2001/XMLSchema#string

Emma J McGhie

http://www.w3.org/2001/XMLSchema#string

Ole Hørning

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Peter J Hume

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Tao Liu

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P2860

ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

Structure and control of the actin regulatory WAVE complex

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes

The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

A nucleator arms race: cellular control of actin assembly

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35

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108

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Vassilis Koronakis

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2011-08-15T00:00:00Z

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51574081

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21844371

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3167530

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