The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity
about
The major human and mouse granzymes are structurally and functionally divergentThe three-dimensional structure of the N-acetylglucosamine-6-phosphate deacetylase, NagA, from Bacillus subtilis: a member of the urease superfamilyProtein sectors: evolutionary units of three-dimensional structureGranzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme BCharacterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificityThe cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics.Proteomic profiling of proteases: tools for granzyme degradomics.Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.Granzyme A activates another way to dieImplantation serine proteinase 1 exhibits mixed substrate specificity that silences signaling via proteinase-activated receptorsProtein multifunctionality: principles and mechanisms.Death by a thousand cuts: granzyme pathways of programmed cell deathGranzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70.Implantation serine proteinase 2 is a monomeric enzyme with mixed serine proteolytic activity and can silence signalling via proteinase activated receptors.Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation.The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease.Controversies in granzyme biology.Proteolytic clipping of histone tails: the emerging role of histone proteases in regulation of various biological processes.Blessing or curse? Proteomics in granzyme research.Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death.Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs.SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin.Granzyme A expression reveals distinct cytolytic CTL subsets following influenza A virus infection.Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A.
P2860
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P2860
The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The oligomeric structure of hu ...... extended substrate specificity
@ast
The oligomeric structure of hu ...... extended substrate specificity
@en
The oligomeric structure of hu ...... extended substrate specificity
@nl
type
label
The oligomeric structure of hu ...... extended substrate specificity
@ast
The oligomeric structure of hu ...... extended substrate specificity
@en
The oligomeric structure of hu ...... extended substrate specificity
@nl
prefLabel
The oligomeric structure of hu ...... extended substrate specificity
@ast
The oligomeric structure of hu ...... extended substrate specificity
@en
The oligomeric structure of hu ...... extended substrate specificity
@nl
P2093
P356
P1476
The oligomeric structure of hu ...... extended substrate specificity
@en
P2093
Charles S Craik
David H Goetz
Jennifer L Harris
Jessica K Bell
Robert J Fletterick
Sami Mahrus
P2888
P304
P356
10.1038/NSB944
P407
P577
2003-07-01T00:00:00Z
P5875
P6179
1040683288