Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis
about
Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamilyCrystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branchingStructure ofStaphylococcus aureus1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoASpecificity and Reactivity in Menaquinone Biosynthesis: The Structure of Escherichia coli MenD (2-Succinyl-5-Enolpyruvyl-6-Hydroxy-3-Cyclohexadiene-1-Carboxylate Synthase)Structural and Biophysical Characterization of BoxC from Burkholderia xenovorans LB400: A NOVEL RING-CLEAVING ENZYME IN THE CROTONASE SUPERFAMILYMechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily MemberLigand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analoguesBiosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsStructure of 6-oxo camphor hydrolase H122A mutant bound to its natural product, (2S,4S)-alpha-campholinic acid: mutant structure suggests an atypical mode of transition state binding for a crotonase homologStructural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesisA Methyl 4-Oxo-4-phenylbut-2-enoate with in Vivo Activity against MRSA that Inhibits MenB in the Bacterial Menaquinone Biosynthesis PathwayMechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesisSynthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosisPartial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJA bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coliDomain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase3D complex: a structural classification of protein complexesBiosynthesis of Menaquinone (Vitamin K2) and Ubiquinone (Coenzyme Q)Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli.Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediateA dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.Stable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesisMechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agentsCloning, expression, purification, crystallization and preliminary X-ray crystallographic study of DHNA synthetase from Geobacillus kaustophilus.Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens.Energy metabolism and drug efflux in Mycobacterium tuberculosisMenA is a promising drug target for developing novel lead molecules to combat Mycobacterium tuberculosis.Reviews on 1,4-naphthoquinones from Diospyros L.Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.Development of new antituberculous agents based on new drug targets and structure-activity relationship.CoA Adducts of 4-Oxo-4-Phenylbut-2-enoates: Inhibitors of MenB from the M. tuberculosis Menaquinone Biosynthesis Pathway.Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.Cyclohexane carboxylate and benzoate formation from crotonate in Syntrophus aciditrophicus.Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics.
P2860
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P2860
Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@ast
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@en
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@nl
type
label
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@ast
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@en
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@nl
prefLabel
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@ast
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@en
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@nl
P2093
P2860
P921
P3181
P356
P1476
Crystal structure of Mycobacte ...... yme in vitamin K2 biosynthesis
@en
P2093
Carl Machutta
James J Truglio
Karsten Theis
Ramona Gajda
Yuguo Feng
P2860
P304
P3181
P356
10.1074/JBC.M307399200
P407
P577
2003-10-24T00:00:00Z