Energy metabolism and drug efflux in Mycobacterium tuberculosis
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Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infectionsMycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistanceSynergistic Effect of Oleanolic Acid on Aminoglycoside Antibiotics against Acinetobacter baumanniiIon Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosisInterplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosisReduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis.The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress.RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates.Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo.Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action.Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery.A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection.Susceptibility of Mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c.Linezolid Dose That Maximizes Sterilizing Effect While Minimizing Toxicity and Resistance Emergence for Tuberculosis.Imaging the NADH:NAD(+) Homeostasis for Understanding the Metabolic Response of Mycobacterium to Physiologically Relevant Stresses.Antibiotic Bactericidal Activity Is Countered by Maintaining pH Homeostasis in Mycobacterium smegmatis.Whole genome sequence analysis of multidrug-resistant Mycobacterium tuberculosis Beijing isolates from an outbreak in Thailand.Commentary: Superoxide Generation and Its Involvement in the Growth of Mycobacterium smegmatis.The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis.Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function.New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.The anti-mycobacterial activity of the cytochrome bcc inhibitor Q203 can be enhanced by small-molecule inhibition of cytochrome bd.Verapamil targets membrane energetics in Mycobacterium tuberculosis.Indolylalkyltriphenylphosphonium Analogues Are Membrane-Depolarizing Mycobactericidal Agents.Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment.Bioenergetics of Mycobacterium: An Emerging Landscape for Drug Discovery.Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains.RepTB: a gene ontology based drug repurposing approach for tuberculosis.Challenging the Drug-Likeness Dogma for New Drug Discovery in TuberculosisEfflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity
P2860
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P2860
Energy metabolism and drug efflux in Mycobacterium tuberculosis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 March 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Energy metabolism and drug efflux in Mycobacterium tuberculosis
@en
Energy metabolism and drug efflux in Mycobacterium tuberculosis.
@nl
type
label
Energy metabolism and drug efflux in Mycobacterium tuberculosis
@en
Energy metabolism and drug efflux in Mycobacterium tuberculosis.
@nl
prefLabel
Energy metabolism and drug efflux in Mycobacterium tuberculosis
@en
Energy metabolism and drug efflux in Mycobacterium tuberculosis.
@nl
P2093
P2860
P356
P1476
Energy metabolism and drug efflux in Mycobacterium tuberculosis
@en
P2093
Gail E Louw
Paul D van Helden
Philippa A Black
Thomas C Victor
P2860
P304
P356
10.1128/AAC.02293-13
P407
P577
2014-03-10T00:00:00Z