The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
about
Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexinReceptor complexes for each of the Class 3 SemaphorinsCrystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptorStructural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1A novel adaptation of the integrin PSI domain revealed from its crystal structureStructural basis of semaphorin-plexin signallingBiology and function of neuroimmune semaphorins 4A and 4DUnderstanding cell signalling systems: paving the way for new therapiesMET: a critical player in tumorigenesis and therapeutic targetBinding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector DomainCrystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine KinaseNeuropilins lock secreted semaphorins onto plexins in a ternary signaling complexPlexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced DimerizationSemaphorin-7A is an erythrocyte receptor for P. falciparum merozoite-specific TRAP homolog, MTRAPTransmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulationsSemaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motifRequirement of the transmembrane semaphorin Sema4C for myogenic differentiationSemaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.Semaphorin 7A inhibits platelet production from CD34+ progenitor cells.Control of bone resorption by semaphorin 4D is dependent on ovarian function.High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling moleculeThe Hepatocyte Growth Factor Receptor: Structure, Function and Pharmacological Targeting in CancerSmall-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapiesMinding the gaps to promote thrombus growth and stabilityDiverse functions for the semaphorin receptor PlexinD1 in development and disease.Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeuticsRegulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injurySemaphorins in angiogenesis and tumor progression.To move or not to move? Semaphorin signalling in cell migration.Structural mechanisms of plexin signalingSemaphorins: a new class of immunoregulatory molecules.Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell SurfaceSerum Sema4D levels are associated with lumbar spine bone mineral density and bone turnover markers in patients with postmenopausal osteoporosisIdentification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in plateletsCharacterization of SEMA3A-encoded semaphorin as a naturally occurring Kv4.3 protein inhibitor and its contribution to Brugada syndrome.Targeting the HGF/Met signaling pathway in cancer therapyNeuropilin-2 promotes extravasation and metastasis by interacting with endothelial α5 integrinSema4D localizes to synapses and regulates GABAergic synapse development as a membrane-bound molecule in the mammalian hippocampus.A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.
P2860
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P2860
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The ligand-binding face of the ...... on crystal structure of SEMA4D
@ast
The ligand-binding face of the ...... on crystal structure of SEMA4D
@en
The ligand-binding face of the ...... on crystal structure of SEMA4D
@nl
type
label
The ligand-binding face of the ...... on crystal structure of SEMA4D
@ast
The ligand-binding face of the ...... on crystal structure of SEMA4D
@en
The ligand-binding face of the ...... on crystal structure of SEMA4D
@nl
prefLabel
The ligand-binding face of the ...... on crystal structure of SEMA4D
@ast
The ligand-binding face of the ...... on crystal structure of SEMA4D
@en
The ligand-binding face of the ...... on crystal structure of SEMA4D
@nl
P2093
P50
P356
P1476
The ligand-binding face of the ...... on crystal structure of SEMA4D
@en
P2093
Christopher A Love
E Yvonne Jones
Robert M Esnouf
Simon J Davis
P2888
P356
10.1038/NSB977
P407
P577
2003-10-01T00:00:00Z
P6179
1022651083