Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors.
about
Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformationThe R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195 † ‡Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutantStructures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand bindingProtein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthaseAnalysis of mRNA recognition by human thymidylate synthase.Chemical shift imprint of intersubunit communication in a symmetric homodimer.Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductaseMultisubstrate adduct inhibitors: drug design and biological tools.Inhibitory effects of neochamaejasmin B on P-glycoprotein in MDCK-hMDR1 cells and molecular docking of NCB binding in P-glycoprotein.Human thymidylate synthase with loop 181-197 stabilized in an inactive conformation: ligand interactions, phosphorylation, and inhibition profiles.Selective peptide inhibitors of bifunctional thymidylate synthase-dihydrofolate reductase from Toxoplasma gondii provide insights into domain-domain communication and allosteric regulation.Evolution of metamorphism in thymidylate synthases within the primate lineages.Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach.The active-inactive transition of human thymidylate synthase: Targeted molecular dynamics simulations
P2860
Q27646380-E41A4A0C-DE01-49B0-91AD-DB3E27C20712Q27650172-460829DE-D04C-41F7-95E5-DD48BEF88543Q27650302-2ED5A7AD-E1A0-4BBC-A641-6956440FE091Q27666489-C5F5710B-F888-45C7-AEE3-47205374F242Q27671027-8F2A44B7-E819-4D6E-AEC0-48379C08D3ECQ34761753-921AC430-DF4D-451A-9E51-206029ED6425Q37213768-78A152B2-4CEA-45D3-8F34-7C11D9AB3EF9Q37623850-66F49F1B-6B1C-41F9-871A-D522C9923F67Q37632419-D64618E9-2824-4385-830F-12437EF0A4B9Q41440285-F31C8E2A-BB42-47A8-8EA1-51D763BC475CQ41942166-D90DCF3F-55C6-44F0-A12F-28D97180EF30Q42632086-6CEB318D-140E-488E-B101-5E0AD3221144Q48059989-1F9C1F0D-7D2D-4C2D-B5AE-C5DABB5F7913Q55299217-583B2A57-D72C-43A8-B3AF-CF03464E2620Q57975285-42C4F4B0-0260-478D-8F41-3745112D281C
P2860
Cooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cooperative Inhibition of Huma ...... nd Allosteric Inhibitors † , ‡
@nl
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@ast
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@en
type
label
Cooperative Inhibition of Huma ...... nd Allosteric Inhibitors † , ‡
@nl
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@ast
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@en
prefLabel
Cooperative Inhibition of Huma ...... nd Allosteric Inhibitors † , ‡
@nl
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@ast
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@en
P2860
P356
P1433
P1476
Cooperative inhibition of huma ...... ing and allosteric inhibitors.
@en
P2093
Leslie L Lovelace
Lydia M Gibson
P2860
P304
P356
10.1021/BI061309J
P407
P577
2007-02-13T00:00:00Z