about
Human liver glycogen phosphorylase inhibitors bind at a new allosteric siteCloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptorFull-length human glutaminase in complex with an allosteric inhibitorBenzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding modeAllosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sitesMolecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signalingLipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolaseAllosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidatesPhosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits.Loop 5-directed compounds inhibit chimeric kinesin-5 motors: implications for conserved allosteric mechanismsDivergent allosteric control of the IRE1α endoribonuclease using kinase inhibitorsAn allosteric enhancer of M₄ muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaineRational design of potent, small, synthetic allosteric inhibitors of thrombinPositive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporterInduced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcriptionCyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonistsPotent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance ProfilingNonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substratesThe growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABLSmall molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain.Structure–activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinaseAllosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistryCrystal structure of HslUV complexed with a vinyl sulfone inhibitor: corroboration of a proposed mechanism of allosteric activation of HslV by HslUAnilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallographyNon-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP siteThiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic studyCooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors.Discovery and preclinical characterization of the cyclopropylindolobenzazepine BMS-791325, a potent allosteric inhibitor of the hepatitis C virus NS5B polymeraseIdentification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymeraseAllosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinasesStructure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding siteThermodynamic characterization of allosteric glycogen phosphorylase inhibitorsAllosteric Coupling between the Lid and Interdomain Linker in DnaK Revealed by Inhibitor Binding StudiesDevelopment of thioquinazolinones, allosteric Chk1 kinase inhibitorsA new screening assay for allosteric inhibitors of cSrcStructure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymeraseNovel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICSDevelopment of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitorsSubstituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants
P921
Q24290218-93FA589C-6EB9-4829-8925-48E5E281D794Q24295169-1B9CD5F5-15A1-4903-AFBB-A75970EFFA49Q24295587-D7176861-DF79-4D05-9E24-7C25162841C1Q24302297-A0C44E93-C9BC-417F-A0CC-B2E77BB11D11Q24316275-B130DB65-8765-4A5F-B302-4AD606E09FE6Q24338718-08F15DEA-1E51-41D4-A642-4B6ADDC1A4F6Q24546215-49DA819D-E8BB-4724-9CC3-AF5731CCDCFFQ24548323-8E534376-5719-4919-9235-28951FA0053DQ24562656-94B36D65-C6A0-47E1-A2D3-7F083718C38BQ24598085-CB2BA76D-E3E2-4072-A905-F738EA274EB6Q24606387-6B282E8A-CC9E-4E4E-B367-6C43813A9195Q24608616-7F497282-A50E-4A72-AADA-279224D79038Q24623182-B6867EA7-0067-4FED-B41F-B85D08907014Q24644993-A40F4A4E-78F6-4CEA-BE9B-4A402B69A5D9Q24646744-C2EDACD1-8CB5-446B-9A77-830EA268D165Q24681622-5262FD98-80CB-4865-84B2-5222B8BB6629Q26247399-E244022F-399A-4362-93D6-CB6582E01873Q26853319-33CFD8ED-8A14-46C5-B2B2-711B0032FDAFQ26866312-8A4D4026-E1F2-4BDA-99D0-D31E36EEEB6EQ27324411-1190C7BC-51F6-4FEC-AE9C-99743C2A41D4Q27490391-650E9A62-72F2-43CB-972B-325ADC26A7C6Q27621434-74C4EA4C-33C4-4368-8771-AA42D6D307C3Q27639130-A3E94B92-DB9E-453B-92B9-66F5BD8D913CQ27639512-BCF6D26D-4AE9-450B-BB6F-4DCD806A86E0Q27640261-27F0AF3B-5514-4C2A-A763-88CC0D95D48EQ27641372-42869F19-5C02-467F-9F19-58F513039FE8Q27643731-AE2A2FB2-257B-43AF-A469-A4E460FCBEBFQ27643812-D89982DF-FE33-4416-8390-DDEFA4D7C594Q27644285-F4DCB6C5-FF42-47EE-B0CC-C34B5C92E1E6Q27644326-3E6DEC99-1779-4562-8E5E-AD33C1A27EAAQ27644421-1B71F68A-AD5F-4D52-9607-FF1F7971AC9FQ27649707-5EE888E7-215C-49F8-8A02-5AA1524E1AE5Q27650179-F029AB88-F2B9-4E56-8227-D20D6D33E855Q27653249-C36A89BF-4955-4669-A484-2DA587AD1410Q27653474-86E51F35-EF0E-4C06-93E6-A5DAC17EDFA7Q27655292-A290FF1A-F794-44D1-B7DC-5B471E603812Q27655827-F970020E-6551-49EC-9840-748F6F70D221Q27655990-87DBD440-7A12-4BE0-A237-21B4DDA906B9Q27656310-A0563A39-6E27-401B-B99B-F7001845F20CQ27656707-81EBB5F0-AD02-4A33-8120-EE815D8365D1
P921
description
molecule that binds to a macro ...... ther molecule becomes inactive
@en
name
allosteric inhibitor
@en
type
label
allosteric inhibitor
@en
prefLabel
allosteric inhibitor
@en