Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants
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Structural basis for androgen specificity and oestrogen synthesis in human aromataseKey Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A EnzymesX-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: Insights into compensatory rearrangements of the binding pocketStructural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Identification of amino acid residues involved in 4-chloroindole 3-hydroxylation by cytochrome P450 2A6 using screening of random libraries.Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coliBioactivities of berberine metabolites after transformation through CYP450 isoenzymes.Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compoundsElucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approachesEffect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.Substrate binding to cytochromes P450.Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast.Conformational diversity and ligand tunnels of mammalian cytochrome P450s.Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl.Point mutation of cytochrome P450 2A6 (a polymorphic variant CYP2A6.25) confers new substrate specificity towards flavonoids.Structure and Dynamics of Human Drug-Metabolizing Cytochrome P450 EnzymesComputational prediction of drug binding and rationalisation of selectivity towards cytochromes P450
P2860
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P2860
Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@ast
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@en
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@nl
type
label
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@ast
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@en
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@nl
prefLabel
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@ast
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@en
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@nl
P2093
P2860
P3181
P1476
Structural insight into the al ...... an cytochrome P450 2A6 mutants
@en
P2093
C David Stout
Eric F Johnson
Mei-Hui Hsu
Stefaan Sansen
P2860
P304
P3181
P356
10.1016/J.ABB.2007.04.028
P407
P577
2007-08-15T00:00:00Z