Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase

Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase

Item
http://www.wikidata.org/entity/Q27649522
Structural Characterization of the Molecular Events during a Slow Substrate–Product Transition in Orotidine 5′-Monophosphate DecarboxylaseStructural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylaseNovel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate DecarboxylaseAtomic Resolution Structure of the Orotidine 5'-Monophosphate Decarboxylase Product Complex Combined with Surface Plasmon Resonance Analysis: IMPLICATIONS FOR THE CATALYTIC MECHANISMSubstrate Distortion Contributes to the Catalysis of Orotidine 5′-Monophosphate DecarboxylaseThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsProton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituentAntimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisPlasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.Electrophilic aromatic selenylation: new OPRT inhibitors.Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolismPurine and pyrimidine pathways as targets in Plasmodium falciparum.Using catalytic atom maps to predict the catalytic functions present in enzyme active sites.5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.Design of inhibitors of ODCase.Synthesis of sulfone-based nucleotide isosteres: identification of CMP-sialic acid synthetase inhibitors.Synthesis of orotidine by intramolecular nucleosidation.
P2860

Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase

Item
http://www.wikidata.org/entity/Q27649522
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure-activity relationshi ...... ne monophosphate decarboxylase
@ast
Structure-activity relationshi ...... ne monophosphate decarboxylase
@en
Structure-activity relationshi ...... ne monophosphate decarboxylase
@nl
type
label
Structure-activity relationshi ...... ne monophosphate decarboxylase
@ast
Structure-activity relationshi ...... ne monophosphate decarboxylase
@en
Structure-activity relationshi ...... ne monophosphate decarboxylase
@nl
prefLabel
Structure-activity relationshi ...... ne monophosphate decarboxylase
@ast
Structure-activity relationshi ...... ne monophosphate decarboxylase
@en
Structure-activity relationshi ...... ne monophosphate decarboxylase
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Structure-activity relationshi ...... ne monophosphate decarboxylase
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698