Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site
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A web server for predicting inhibitors against bacterial target GlmU proteinStructure and function of GlmU fromMycobacterium tuberculosisStructure ofN-acetylglucosamine-1-phosphate uridyltransferase (GlmU) fromMycobacterium tuberculosisin a cubic space groupIn Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzaeGenetic and structural validation ofAspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal targetAn aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding modeKinetic modelling of GlmU reactions - prioritization of reaction for therapeutic applicationHigh-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU.Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolyticaStructures of Bacteroides fragilis uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (BfLpxA)Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Viable screening targets related to the bacterial cell wall.Dynamic profile analysis to characterize dynamics-driven allosteric sites in enzymes.GlmU (N-acetylglucosamine-1-phosphate uridyltransferase) bound to three magnesium ions and ATP at the active sitePurification and biochemical characterisation of GlmU from Yersinia pestis.The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU.A structural biology view of target drugability.Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU).
P2860
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P2860
Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site
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2008 nî lūn-bûn
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2008 թուականի Մարտին հրատարակուած գիտական յօդուած
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2008 թվականի մարտին հրատարակված գիտական հոդված
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年论文
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Structure of a small-molecule ...... als an allosteric binding site
@ast
Structure of a small-molecule ...... als an allosteric binding site
@en
Structure of a small-molecule ...... als an allosteric binding site
@nl
type
label
Structure of a small-molecule ...... als an allosteric binding site
@ast
Structure of a small-molecule ...... als an allosteric binding site
@en
Structure of a small-molecule ...... als an allosteric binding site
@nl
prefLabel
Structure of a small-molecule ...... als an allosteric binding site
@ast
Structure of a small-molecule ...... als an allosteric binding site
@en
Structure of a small-molecule ...... als an allosteric binding site
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure of a small-molecule ...... als an allosteric binding site
@en
P2093
Igor Mochalkin
Lakshmi Narasimhan
Laura McDowell
Michael Melnick
Sandra Lightle
Steven Vanderroest
P2860
P304
P3181
P356
10.1110/PS.073271408
P50
P577
2008-01-24T00:00:00Z