Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor
about
Crystal Structure and Acyl Chain Selectivity of Escherichia coli LpxD, the N -Acyltransferase of Lipid A BiosynthesisStructures of Metal-Substituted Human Histone Deacetylase 8 Provide Mechanistic Inferences on Biological Function,Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic DesignStructure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090,Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffoldStructure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton TransferStructural Basis of the Promiscuous Inhibitor Susceptibility of Escherichia coli LpxCProteomics-based identification of differentially abundant proteins reveals adaptation mechanisms of Xanthomonas citri subsp. citri during Citrus sinensis infection.Assignment of 1H, 13C and 15N backbone resonances of Escherichia coli LpxC bound to L-161,240A new class of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitors for the treatment of Gram-negative infections: PCT application WO 2008027466.Update on carbohydrate-containing antibacterial agents.Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.Crystal structure of A. aeolicus LpxC with bound product suggests alternate deacetylation mechanism.Activation of Escherichia coli UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase by Fe2+ yields a more efficient enzyme with altered ligand affinity.Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.
P2860
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P2860
Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor
description
2008 nî lūn-bûn
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2008 թուականի Մարտին հրատարակուած գիտական յօդուած
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2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@ast
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@en
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@nl
type
label
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@ast
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@en
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@nl
prefLabel
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@ast
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@en
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of LpxC from ...... the potent BB-78485 inhibitor
@en
P2093
Igor Mochalkin
John D Knafels
Sandra Lightle
P2860
P356
10.1110/PS.073324108
P577
2008-03-01T00:00:00Z