Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

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Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets.Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors

P2860

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P2860

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

Item

http://www.wikidata.org/entity/Q38846788

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

@zh-cn

name

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

@en

type

Item

label

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

@en

prefLabel

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

@en

P1476

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

@en

P2093

Alice L Erwin

http://www.w3.org/2001/XMLSchema#string

P2860

Transport of lipopolysaccharide across the cell envelope: the long road of discovery

Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesis

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding

Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor

Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design

Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold

Design and synthesis of potent Gram-negative specific LpxC inhibitors

Potent inhibitors of LpxC for the treatment of Gram-negative infections

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections

Synthesis, Structure, and Antibiotic Activity of Aryl-Substituted LpxC Inhibitors

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scholarly article

P356

10.1101/CSHPERSPECT.A025304

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2016-07-01T00:00:00Z

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27235477

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P921

lipopolysaccharide

P932

4930914

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Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

about

P2860

P2860

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

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P356

P433

P478

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P433

P478

P577

P698

P921

P932