Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides - Wikidata - wikimedia - TriplyDB

Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides

Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides

http://www.wikidata.org/entity/Q27650227

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Crystal Structure and Computational Analyses Provide Insights into the Catalytic Mechanism of 2,4-Diacetylphloroglucinol Hydrolase PhlG from Pseudomonas fluorescens Structure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne Biosynthesis The polyketide cyclase RemF from Streptomyces resistomycificus contains an unusual octahedral zinc binding site Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization Structural and Biochemical Characterization of ZhuI Aromatase/Cyclase from the R1128 Polyketide Pathway Insight into the Molecular Basis of Aromatic Polyketide Cyclization: Crystal Structure and in Vitro Characterization of WhiE-ORFVI A Thermoacidophile-Specific Protein Family, DUF3211, Functions as a Fatty Acid Carrier with Novel Binding Mode Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19 Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides Expanding our understanding of sequence-function relationships of type II polyketide biosynthetic gene clusters: bioinformatics-guided identification of Frankiamicin A from Frankia sp. EAN1pec Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response.Solution structure and function of YndB, an AHSA1 protein from Bacillus subtilis Structural enzymology of polyketide synthases.Cyclization of aromatic polyketides from bacteria and fungi Discovery of binding proteins for a protein target using protein-protein docking-based virtual screening.The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition New insights into the formation of fungal aromatic polyketides.Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027 Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters.Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases Rational reprogramming of fungal polyketide first-ring cyclization Opportunities for enzyme engineering in natural product biosynthesis.Structural insights into nonribosomal peptide enzymatic assembly lines Biosynthesis of aromatic polyketides in bacteria.PKS and NRPS release mechanisms.The structural role of the carrier protein--active controller or passive carrier.Structural and functional aspects of PR-10 proteins.A Novel Class of Plant Type III Polyketide Synthase Involved in Orsellinic Acid Biosynthesis from Rhododendron dauricum Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters.Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family.Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin.Synthesis, double-helix formation, and higher-assembly formation of chiral polycyclic aromatic compounds: conceptual development of polyketide aldol synthesis.β-chain extension: a new mode of carbon-carbon bond formation and chain extension by polyketide synthases.Chemical shift assignments of polyketide cyclase_like protein CGL2373 from Corynebacterium glutamicum.The International Conference of Natural Product Biosynthesis (ICNPB, 8th US-Japan seminar on the Biosynthesis of Natural Products).Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256.

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Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Crystal structure and function ...... ficity of aromatic polyketides

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Brian Douglas Ames

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Peter Smith

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Shiou-Chuan Tsai

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Thanh Vu

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Tyler Paz Korman

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Wenjun Zhang

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Yi Tang

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P2860

The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

Automated MAD and MIR structure solution

Improved protein-ligand docking using GOLD

Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation.

Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily.

Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes

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10.1073/PNAS.0709223105

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105

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5464752

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18388203

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crystal structure

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2291100

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