A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability
about
Identification of Aurora-A Inhibitors by Ligand and Structure-Based Virtual Screening.Advances in Aurora kinase inhibitor patents.Aurora kinase inhibitors: progress towards the clinicZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.The molecular mechanism studies of chirality effect of PHA-739358 on Aurora kinase A by molecular dynamics simulation and free energy calculations.Combined 3D-QSAR modeling and molecular docking studies on pyrrole-indolin-2-ones as Aurora A kinase inhibitors.Classification of Aurora-A Kinase Inhibitors Using Self-Organizing Map (SOM) and Support Vector Machine (SVM).Some insights into the binding mechanism of Aurora B kinase gained by molecular dynamics simulation.3D-QSAR and molecular docking studies of azaindole derivatives as Aurora B kinase inhibitors.
P2860
Q30009428-54FD176A-11CE-4D37-A78C-8723E173583BQ37481268-7C90454B-FCEC-4004-BD60-998445917748Q37986455-74EF63DE-2BC3-4E15-BD2A-67501F3E408FQ39620050-8485F7C9-23ED-4A6E-9174-D9B35719B0ADQ39794961-863A8107-0C72-46AC-B1A1-0E3BAC0A5A20Q41984158-7788FFCF-FE47-41BA-AF02-001E1C7D5691Q47396117-6A6C11A2-3105-4D46-B5B4-74E6BF67027DQ47696164-FBD08550-D0B6-4F52-86C5-6A870C3DF604Q54657116-01835DAF-30E0-44FD-95E7-D0ED8F977A8D
P2860
A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@ast
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@en
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@nl
type
label
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@ast
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@en
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@nl
prefLabel
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@ast
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@en
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@nl
P2093
P50
P356
P1476
A pentacyclic aurora kinase in ...... tency and oral bioavailability
@en
P2093
Angela McNutt
Anja Limberg
Bernhard Goller
Bing-Yan Zhu
Birong Zhang
Brian Safina
Carter Fields
Christian Wiesmann
Dan Burdick
P304
P356
10.1021/JM800052B
P407
P577
2008-08-14T00:00:00Z