Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction
about
Crystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suumThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsPharmacophore modeling for anti-Chagas drug design using the fragment molecular orbital method.The Open Form Inducer Approach for Structure-Based Drug Design.Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions.Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis.Insights into the mechanism of oxidation of dihydroorotate to orotate catalysed by human class 2 dihydroorotate dehydrogenase: a QM/MM free energy study.Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanilDisruption of the proton relay network in the class 2 dihydroorotate dehydrogenase from Escherichia coli.Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli.Computational study of the mechanism of half-reactions in class 1A dihydroorotate dehydrogenase from Trypanosoma cruzi.Fresh insights into the pyrimidine metabolism in the trypanosomatids.The unassembled flavoprotein subunits of human and bacterial complex II have impaired catalytic activity and generate only minor amounts of ROS.Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma brucei.Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions
P2860
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P2860
Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@ast
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@en
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@nl
type
label
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@ast
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@en
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@nl
prefLabel
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@ast
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@en
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@nl
P2093
P50
P356
P1433
P1476
Structures of Trypanosoma cruz ...... idation and fumarate reduction
@en
P2093
Hironari Shimizu
Kimitoshi Sakamoto
Shigeharu Harada
Takashi Aoki
Takeshi Nara
Tomoo Shiba
P304
P356
10.1021/BI800413R
P407
P577
2008-10-14T00:00:00Z