Insights into the mechanism of oxidation of dihydroorotate to orotate catalysed by human class 2 dihydroorotate dehydrogenase: a QM/MM free energy study.

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Insights into the mechanism of oxidation of dihydroorotate to orotate catalysed by human class 2 dihydroorotate dehydrogenase: a QM/MM free energy study.

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Insights into the mechanism of ...... se: a QM/MM free energy study.

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Insights into the mechanism of ...... se: a QM/MM free energy study.

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Insights into the mechanism of ...... se: a QM/MM free energy study.

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P1476

Insights into the mechanism of ...... ase: a QM/MM free energy study

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P2093

Adrian E Roitberg

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Cláudio Nahum Alves

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P2860

Divergent evolution of pyrimidine biosynthesis between anaerobic and aerobic yeasts

The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function

Leflunomide: mode of action in the treatment of rheumatoid arthritis

Comparison of simple potential functions for simulating liquid water

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

E. coli dihydroorotate dehydrogenase reveals structural and functional distinctions between different classes of dihydroorotate dehydrogenases

Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function

Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies

Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction

Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery

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17790-17796

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scholarly article

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10.1039/C5CP02016F

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English

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P478

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José Rogério A Silva

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2015-06-19T00:00:00Z

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26087682

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