Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4 : DIABETES GENE PRODUCT
about
Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activationMultidomain integration in the structure of the HNF-4α nuclear receptor complexAminopeptidases do not directly degrade tau protein.MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.TACO: a general-purpose tool for predicting cell-type-specific transcription factor dimers.Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays.The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase.Understanding nuclear receptor form and function using structural biologyProteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID.Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.Transcriptional Regulation of CYP2D6 Expression.Preventing Gut Leakiness and Endotoxemia Contributes to the Protective Effect of Zinc on Alcohol-Induced Steatohepatitis in Rats.Comprehensive screening for monogenic diabetes in 89 Japanese children with insulin-requiring antibody-negative type 1 diabetes.Probing the effect of MODY mutations near the co-activator-binding pocket of HNF4α.Loss-of-function mutations in Zn-finger DNA-binding domain of HNF4A cause aberrant transcriptional regulation in liver cancer.
P2860
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P2860
Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4 : DIABETES GENE PRODUCT
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@ast
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@en
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@nl
type
label
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@ast
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@en
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@nl
prefLabel
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@ast
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@en
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@nl
P2093
P2860
P356
P1476
Structural Basis of Natural Pr ...... , HNF4 : DIABETES GENE PRODUCT
@en
P2093
Brandon C Adkins
Geun Bae Rha
Guangteng Wu
Manana Melikishvili
Michael G Fried
Young-In Chi
P2860
P304
P356
10.1074/JBC.M806213200
P407
P577
2008-11-28T00:00:00Z