Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays.
about
Using protein-binding microarrays to study transcription factor specificity: homologs, isoforms and complexesThe cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked mannerMultidomain integration in the structure of the HNF-4α nuclear receptor complexCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsDiscovery and characterization of human exonic transcriptional regulatory elementsAnks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cellsRole of Hepatic-Specific Transcription Factors and Polycomb Repressive Complex 2 during Induction of Fibroblasts to Hepatic FateNetwork insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a reviewABCC6 expression is regulated by CCAAT/enhancer-binding protein activating a primate-specific sequence located in the first intron of the geneWhat are nuclear receptor ligands?Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis.Alterations of epigenetic signatures in hepatocyte nuclear factor 4α deficient mouse liver determined by improved ChIP-qPCR and (h)MeDIP-qPCR assays.Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregatesDiscovering networks of perturbed biological processes in hepatocyte culturesExpression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4αThe ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.Protein-binding microarray analysis of tumor suppressor AP2α target gene specificity.Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity.Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsNext-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.HNF4α--role in drug metabolism and potential drug target?A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden.Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virusModification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.Molecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetesDisease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetesIdentification of Annexin A4 as a hepatopancreas factor involved in liver cell survival.Complex interplay between the lipin 1 and the hepatocyte nuclear factor 4 α (HNF4α) pathways to regulate liver lipid metabolismTissue-specific regulation of mouse microRNA genes in endoderm-derived tissuesFraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions.The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the LiverComprehensive gene expression profiling reveals synergistic functional networks in cerebral vessels after hypertension or hypercholesterolemia.An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example.HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells.Resetting the transcription factor network reverses terminal chronic hepatic failure.A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver.
P2860
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P2860
Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Integrated approach for the id ...... g protein binding microarrays.
@ast
Integrated approach for the id ...... g protein binding microarrays.
@en
type
label
Integrated approach for the id ...... g protein binding microarrays.
@ast
Integrated approach for the id ...... g protein binding microarrays.
@en
prefLabel
Integrated approach for the id ...... g protein binding microarrays.
@ast
Integrated approach for the id ...... g protein binding microarrays.
@en
P2093
P2860
P356
P1433
P1476
Integrated approach for the id ...... g protein binding microarrays.
@en
P2093
Chuhu Yang
Eugene Bolotin
Frances M Sladek
Hailing Liao
Jane R Evans
Tuong Chi Ta
Wendy Hwang-Verslues
P2860
P304
P356
10.1002/HEP.23357
P407
P577
2010-02-01T00:00:00Z