Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5 - Wikidata - wikimedia - TriplyDB

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

http://www.wikidata.org/entity/Q27652424

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IRF7: activation, regulation, modification and function Activation of interferon regulatory factor 5 by site specific phosphorylation The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice Clusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability.Toll-like receptor signaling in cell proliferation and survival Structural insights into interferon regulatory factor activation.Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3)IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.IKKβ is an IRF5 kinase that instigates inflammation Interferon regulatory factors: critical mediators of human lupus.A conserved region within interferon regulatory factor 5 controls breast cancer cell migration through a cytoplasmic and transcription-independent mechanism The use of analytical sedimentation velocity to extract thermodynamic linkage.TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.Characterization of common carp (Cyprinus carpio L.) interferon regulatory factor 5 (IRF5) and its expression in response to viral and bacterial challenges.Understanding Transcription Factor Regulation by Integrating Gene Expression and DNase I Hypersensitive Sites.Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain Toward an orofacial gene regulatory network.RETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domain Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus Interferon regulatory factor 5 in the pathogenesis of systemic lupus erythematosus.Epigenetics and the IRFs: a complex interplay in the control of immunity and autoimmunity.Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.Four Promoters of IRF5 Respond Distinctly to Stimuli and are Affected by Autoimmune-Risk Polymorphisms Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection.Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.Corrected and Republished from: The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability.Assembly of human C-terminal Binding Protein (CtBP) into tetramers.

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Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

http://www.wikidata.org/entity/Q27652424

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Insights into interferon regul ...... stal structure of dimeric IRF5

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Insights into interferon regul ...... stal structure of dimeric IRF5

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Insights into interferon regul ...... stal structure of dimeric IRF5

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type

label

Insights into interferon regul ...... stal structure of dimeric IRF5

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Insights into interferon regul ...... stal structure of dimeric IRF5

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Insights into interferon regul ...... stal structure of dimeric IRF5

@nl

prefLabel

Insights into interferon regul ...... stal structure of dimeric IRF5

@ast

Insights into interferon regul ...... stal structure of dimeric IRF5

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Insights into interferon regul ...... stal structure of dimeric IRF5

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Nature Structural & Molecular Biology

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Insights into interferon regul ...... stal structure of dimeric IRF5

@en

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Celia A Schiffer

http://www.w3.org/2001/XMLSchema#string

Hema Srinath

http://www.w3.org/2001/XMLSchema#string

John J Correia

http://www.w3.org/2001/XMLSchema#string

Kai Lin

http://www.w3.org/2001/XMLSchema#string

Katherine A Fitzgerald

http://www.w3.org/2001/XMLSchema#string

Suvana S Lam

http://www.w3.org/2001/XMLSchema#string

Weijun Chen

http://www.w3.org/2001/XMLSchema#string

William E Royer

http://www.w3.org/2001/XMLSchema#string

Zhaozhao Jiang

http://www.w3.org/2001/XMLSchema#string

P2860

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes

The IRF family, revisited

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

X-ray crystal structure of IRF-3 and its functional implications

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1213-20

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scholarly article

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2457046

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10.1038/NSMB.1496

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11

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15

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2008-11-01T00:00:00Z

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23300956

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1026894468

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18836453

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identical protein binding

Interferon regulatory factor 5

crystal structure

structural biology

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2757928

http://www.w3.org/2001/XMLSchema#string