Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases
about
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)Walking to work: roles for class V myosins as cargo transporters.Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.Identification of novel rab27a/melanophilin blockers by pharmacophore-based virtual screening.EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.Rab27a targeting to melanosomes requires nucleotide exchange but not effector bindingA Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin VaThe charge-dipole pocket: a defining feature of signaling pathway GTPase on/off switches.Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranesStructural mechanisms for regulation of membrane traffic by rab GTPasesRab GEFs and GAPs.Rab27 effectors, pleiotropic regulators in secretory pathways.Structure-function analyses of the small GTPase Rab35 and its effector protein centaurin-β2/ACAP2 during neurite outgrowth of PC12 cells.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking.Exploring the iceberg: Prospects of coordinated myosin V and actin assembly functions in transport processes.Multivalency in Rab effector interactions.Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity.A new spectrophotometric method for simple quantification of melanosomal transfer from melanocytes to keratinocytes.The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.bMERB domains are bivalent Rab8 family effectors evolved by gene duplicationRab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes.Cell-free expression of protein complexes for structural biology.The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.Cell-Free Protein Production for Structural Biology
P2860
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P2860
Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@ast
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@en
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@nl
type
label
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@ast
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@en
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@nl
prefLabel
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@ast
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@en
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@nl
P2093
P50
P921
P3181
P1433
P1476
Structural basis for the exclu ...... nophilin for the Rab27 GTPases
@en
P2093
Ayako Sakamoto
Eiko Kanno
Kyoko Hanawa-Suetsugu
Takaho Terada
P304
P3181
P356
10.1016/J.STR.2008.07.014
P577
2008-10-08T00:00:00Z