Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands - Wikidata - wikimedia - TriplyDB

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

http://www.wikidata.org/entity/Q27652795

about

Phospholipid--driven gene regulation Sphingolipid signaling in metabolic disorders Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists PIP kinases define PI4,5P₂signaling specificity by association with effectors PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1 Retinoic acid actions through mammalian nuclear receptors.StarD7 gene expression in trophoblast cells: contribution of SF-1 and Wnt-beta-catenin signaling.Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions.Human male infertility associated with mutations in NR5A1 encoding steroidogenic factor 1 Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.Whole exome sequencing combined with linkage analysis identifies a novel 3 bp deletion in NR5A1 Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.Emerging actions of the nuclear receptor LRH-1 in the gut.Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation.Idiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1.Orphan nuclear receptors as targets for drug development.Inositol polyphosphate multikinase (IPMK) in transcriptional regulation and nuclear inositide metabolism Steroidogenic factor 1 and the central nervous system.Nuclear sphingolipid metabolism.Disentangling biological signaling networks by dynamic coupling of signaling lipids to modifying enzymes.Phospholipid regulation of the nuclear receptor superfamily.Nuclear phosphoinositide regulation of chromatin.Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus.Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc Direct modification and activation of a nuclear receptor-PIP₂ complex by the inositol lipid kinase IPMK.Insights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP).Solution Nuclear Magnetic Resonance Studies of the Ligand-Binding Domain of an Orphan Nuclear Receptor Reveal a Dynamic Helix in the Ligand-Binding Pocket.LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity.

P2860

Q26822791-2335026D-4563-4B11-B970-842DEFB91571 Q26992148-964435C7-99B4-4398-A259-07E0DF3771DB Q27667247-2D9CA8BB-A6D1-48D7-AFB8-103301A7FAF9 Q27678497-EB94AB63-48C9-4D61-B811-9360BE8F4E04 Q27679376-04A0D563-B68C-4490-B7F7-9A71654DDA03 Q28083975-C1269F02-B424-472A-8857-886A5695EBE0 Q28584186-AF5C2EC9-1053-453D-BB2C-F9B829772891 Q30408649-5A3399A9-B4EB-4274-B176-7892863EC275 Q33636890-2DDE3DC0-B63A-430F-9629-CCB8DBFEBBF2 Q33637467-C00E873F-A6FD-4742-BA6B-2070A6DD843B Q33874365-462DE03F-DD14-4EDF-9DA8-A2154E3FECF5 Q34169445-221891B8-01B9-4F58-A2DE-345026993696 Q34356028-DF372FAF-E246-4C3B-B6E6-8C079317C969 Q34408784-D17913D3-2891-4968-8900-F2798A5F36FE Q35149156-432B30AB-1285-4C43-A0DB-A943636F446C Q35220379-E25ABBD3-ECC5-43A8-88CA-C5E005DAA850 Q36296659-C680C75C-7A47-4D57-BADA-FF62E9ECF0BB Q36362832-A953D88D-CA42-437C-85FD-8EC535330010 Q36742648-4AA23D55-2536-4E05-83CD-844F834A3937 Q37375092-4EA1BF2E-2206-4DA2-BF4B-0D48C46B6052 Q37395055-E372B467-C836-4FA5-823F-68DAC0B8D3DF Q37725708-02FFFA87-7D43-47CE-AF54-3B3EE23456C5 Q37737248-E687A79C-7D80-4C3F-A413-E5A1A2EA1AB7 Q37888755-DA4D1A2B-A44B-425E-A665-C1655D876C58 Q37925819-66F6DBEB-B8AC-4CF7-B4D5-30E57B212CE7 Q38157461-4BDDCE70-5433-426A-9328-38F478FA9406 Q39006591-EFE7C095-8BE8-4560-9483-0329CCED9472 Q39159757-85C0B3D9-8E2C-4A46-9897-467DABB4E12A Q41347283-80D934BB-A866-491F-A826-CB4ECD733BA1 Q41956802-63E1686C-8475-4339-90C6-E86EBCBDADF1 Q42077086-C64C82FD-C31E-4159-BE0B-02902B00A174 Q42906910-B07F13EA-36D2-4783-9B10-36E0D31FDE45 Q52652410-445C6555-3239-4F54-9A19-CEC4DC3B2461 Q55021282-81B06CA9-2339-42AC-9344-304671EA58FA

P2860

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

http://www.wikidata.org/entity/Q27652795

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@ast

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@en

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@nl

type

label

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@ast

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@en

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@nl

prefLabel

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@ast

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@en

Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands

@nl

P1433

Q27652795-F3551B85-EBDF-456E-A6B9-DDE1C606FCF8

P1476

Q27652795-BB913D92-48D6-4ABD-93DF-C75D25A90288

P2093

Q27652795-1097F290-14F5-42F7-B5C9-C2E3BFE3A760

Q27652795-32648348-8697-4A11-A689-B766499AFF28

Q27652795-50585943-FE45-43ED-8B8B-341570A41C44

Q27652795-6FC1D923-9CD6-4B81-B308-9D3F3A4EBAA7

Q27652795-91ED222F-EF0C-458C-94A5-3B400561289B

Q27652795-BB7DF97F-F2C2-4A6E-9BAE-05FA99186304

Q27652795-E85D4CD9-D3F4-4E7C-8C45-A6F7800E43B8

P2860

Q27652795-07D44EFF-B621-4E8C-8EA7-8A3E426152B3

Q27652795-09B6886B-073C-40E0-9BF2-A04CC91EA76A

Q27652795-0D05DC05-7D56-4CEB-A580-CB6946F5A9A1

Q27652795-12786FC7-4216-407E-B413-D055D2FC3D54

Q27652795-1B9F67CF-0535-47C7-922C-FC8216F36947

Q27652795-4B45842A-F582-4FE6-AA2F-1AF075CF446B

Q27652795-69004864-E746-4EC1-BAC0-818C32232937

Q27652795-743123BE-FD20-49B6-B96C-B6DAA9559FE4

Q27652795-8C634747-9FA6-4175-A32A-EF277A4AA857

Q27652795-BC9DF81D-C1DE-40A8-BAEA-A4BC4810BD1D

P304

Q27652795-9A651C85-8E01-4C8E-A1F2-9CC6D753996C

P31

Q27652795-3572954E-88D2-48BF-A7B9-D8C32D62A773

P3181

Q27652795-CD296CAE-B77E-46C3-BF1F-8D0D1E58D4AC

P356

Q27652795-0A7DBA03-FFBD-4B4D-A320-7C1F6EC4DEB9

P433

Q27652795-E2E4E8B0-699C-41EC-8BDE-2BC5E0922629

P478

Q27652795-6B5C7362-B5B4-4FE8-AF98-827B03300464

P50

Q27652795-6BB92594-3571-4C5D-99DB-69EB01E8B858

P577

Q27652795-EFEC5E90-10A7-46AB-ABFF-6A60BEC126FF

P5875

Q27652795-DC7CCABE-6101-46D1-8DD1-CEE5C1E41A8E

P698

Q27652795-F5BF1DA1-BF98-4F7A-81F6-77DA4DDE3032

P932

Q27652795-A580FDC1-6C63-443F-A836-287C49528789

P3181

P356

P1433

Molecular Endocrinology

P1476

Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands

@en

P2093

Elena P Sablin

http://www.w3.org/2001/XMLSchema#string

Fang Cai

http://www.w3.org/2001/XMLSchema#string

Holly A Ingraham

http://www.w3.org/2001/XMLSchema#string

Irina N Krylova

http://www.w3.org/2001/XMLSchema#string

Jared G Ingraham

http://www.w3.org/2001/XMLSchema#string

Jon D Williams

http://www.w3.org/2001/XMLSchema#string

Robert J Fletterick

http://www.w3.org/2001/XMLSchema#string

P2860

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

SF-1 a key player in the development and differentiation of steroidogenic tissues

Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1

Partial agonists activate PPARgamma using a helix 12 independent mechanism

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

The coregulator exchange in transcriptional functions of nuclear receptors

Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.

The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1.

Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress.

P304

25-34

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4897205

http://www.w3.org/2001/XMLSchema#string

P356

10.1210/ME.2007-0508

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P50

Raymond D. Blind

P577

2008-11-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23455918

http://www.w3.org/2001/XMLSchema#string

P698

18988706

http://www.w3.org/2001/XMLSchema#string

P932

2646595

http://www.w3.org/2001/XMLSchema#string