General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold
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An update on antibody-based immunotherapies for Clostridium difficile infectionBiotechnological Trends in Spider and Scorpion Antivenom DevelopmentThe use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.In vivo detection of small tumour lesions by multi-pinhole SPECT applying a (99m)Tc-labelled nanobody targeting the Epidermal Growth Factor Receptor.Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural AnalysisImaging Biomarkers in ImmunotherapySingle domain antibodies: promising experimental and therapeutic tools in infection and immunityNovel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary SyndromeThe breadth of cross sub-type neutralisation activity of a single domain antibody to influenza hemagglutinin can be increased by antibody valency.Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid AntibodiesCross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning.Nanobody-coupled microbubbles as novel molecular tracerNanobody: the "magic bullet" for molecular imaging?Modern Technologies for Creating Synthetic Antibodies for Clinical application.Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.Adnectins: engineered target-binding protein therapeuticsNovel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro.Potent neutralization of influenza A virus by a single-domain antibody blocking M2 ion channel protein.A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.Fingerprint-like Analysis of "Nanoantibody" Selection by Phage Display Using Two Helper Phage VariantsEffective Genetic Expression of Nanoantibodies by Recombinant Adenoviral Vector in vitroA novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice.A robust pipeline for rapid production of versatile nanobody repertoires.Isolation and optimization of camelid single-domain antibodies: Dirk Saerens' work on nanobodies.Strategies to stabilize compact folding and minimize aggregation of antibody-based fragmentsContributions of the complementarity determining regions to the thermal stability of a single-domain antibody.Engineered antibody variable and constant domains as therapeutic candidates.A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model.Human recombinant domain antibodies against multiple sclerosis antigenic peptide CSF114(Glc).Stress selections on domain antibodies: 'what doesn't kill you makes you stronger'.Isolation and characterization of antigen-specific alpaca (Lama pacos) VHH antibodies by biopanning followed by high-throughput sequencing.Noninvasive imaging of immune responses.Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.Llama nanoantibodies with therapeutic potential against human norovirus diarrhea.Importance of Hypervariable Region 2 for Stability and Affinity of a Shark Single-Domain Antibody Specific for Ebola Virus NucleoproteinEngineered Autonomous Human Variable DomainsHumanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential.Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells.Generation and characterization of non-competitive furin-inhibiting nanobodies.Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
P2860
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P2860
General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
General strategy to humanize a ...... al humanized nanobody scaffold
@ast
General strategy to humanize a ...... al humanized nanobody scaffold
@en
General strategy to humanize a ...... al humanized nanobody scaffold
@nl
type
label
General strategy to humanize a ...... al humanized nanobody scaffold
@ast
General strategy to humanize a ...... al humanized nanobody scaffold
@en
General strategy to humanize a ...... al humanized nanobody scaffold
@nl
prefLabel
General strategy to humanize a ...... al humanized nanobody scaffold
@ast
General strategy to humanize a ...... al humanized nanobody scaffold
@en
General strategy to humanize a ...... al humanized nanobody scaffold
@nl
P2093
P50
P3181
P356
P1476
General strategy to humanize a ...... al humanized nanobody scaffold
@en
P2093
Cécile Vincke
Katja Conrath
Sergio Martinez-Rodriguez
P304
P3181
P356
10.1074/JBC.M806889200
P407
P577
2009-01-30T00:00:00Z