Generation and characterization of non-competitive furin-inhibiting nanobodies.
about
X-ray Structures of Human Furin in Complex with Competitive InhibitorsInteractions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding.Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer.Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.Proprotein convertase inhibition: Paralyzing the cell's master switches.The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells.Mapping cytoskeletal protein function in cells by means of nanobodies.The proprotein convertase furin in tumour progression.
P2860
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P2860
Generation and characterization of non-competitive furin-inhibiting nanobodies.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@ast
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@en
type
label
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@ast
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@en
prefLabel
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@ast
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@en
P2093
P2860
P356
P1433
P1476
Generation and characterization of non-competitive furin-inhibiting nanobodies.
@en
P2093
Alphons J M Vermorken
Bart Roucourt
Gholamreza H Ghassabeh
Guido David
Iris Lindberg
Jeroen Declercq
John W M Creemers
Jörg Kinne
Sandra Meulemans
Wim J M Van de Ven
P2860
P356
10.1042/BJ20120537
P407
P577
2012-11-01T00:00:00Z