A crystallographic snapshot of tyrosine trans-phosphorylation in action
about
Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cellsThe alternatively spliced acid box region plays a key role in FGF receptor autoinhibitionExploring mechanisms of FGF signalling through the lens of structural biologyCoarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylationThe Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2''-Phosphotransferase-IIa [APH(2'')-IIa] Provide Insights into Substrate Selectivity in the APH(2'') SubfamilyPlasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1Structure of the activating IL-1 receptor signaling complexCracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function MutationsStructural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 MutationOncogenic RET Kinase Domain Mutations Perturb the Autophosphorylation Trajectory by Enhancing Substrate Presentation In transIdentifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinasesMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyStructure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy.Predicting the impact of deleterious mutations in the protein kinase domain of FGFR2 in the context of function, structure, and pathogenesis--a bioinformatics approach.Coupling of transmembrane helix orientation to membrane release of the juxtamembrane region in FGFR3Loss-of-function fibroblast growth factor receptor-2 mutations in melanomaIlluminating the molecular mechanisms of tyrosine kinase inhibitor resistance for the FGFR1 gatekeeper mutation: the Achilles' heel of targeted therapy.Structural and mechanistic insights into the bifunctional enzyme isocitrate dehydrogenase kinase/phosphatase AceK.Effects of FGFR2 kinase activation loop dynamics on catalytic activityTwo FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase CγRegulatory interactions between a bacterial tyrosine kinase and its cognate phosphatase.Grb2, a double-edged sword of receptor tyrosine kinase signalingThe structural biology of the FGF19 subfamilyThe N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor.Tyrosine phosphorylation: thirty years and counting.Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases.BMP-2 and bFGF release and in vitro effect on human osteoblasts after adsorption to bone grafts and biomaterials.FGFR3 biology and skeletal disease.Nuclear magnetic resonance analysis of the conformational state of cancer mutant of fibroblast growth factor receptor 1 tyrosine kinase domain.Structural analysis of the mechanism of phosphorylation of a critical autoregulatory tyrosine residue in FGFR1 kinase domain.A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination.
P2860
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P2860
A crystallographic snapshot of tyrosine trans-phosphorylation in action
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@ast
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@en
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@nl
type
label
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@ast
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@en
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@nl
prefLabel
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@ast
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@en
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@nl
P2093
P2860
P50
P3181
P356
P1476
A crystallographic snapshot of tyrosine trans-phosphorylation in action
@en
P2093
Anna V Eliseenkova
Chong-Feng Xu
Huaibin Chen
Jinghong Ma
Thomas A Neubert
W Todd Miller
Wanqing Li
P2860
P304
P3181
P356
10.1073/PNAS.0807752105
P407
P577
2008-12-16T00:00:00Z