Structure of the activating IL-1 receptor signaling complex
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Structural basis for the specific recognition of IL-18 by its alpha receptorStructural biology of the IL-1 superfamily: key cytokines in the regulation of immune and inflammatory responsesDesign of a superior cytokine antagonist for topical ophthalmic useStructural insights into the interaction of IL-33 with its receptorsIRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assemblyIL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transductionMechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β.Understanding the folding-function tradeoff in proteins.The structural basis for receptor recognition of human interleukin-18Transcriptome analysis of hen preadipocytes treated with an adipogenic cocktail (DMIOA) with or without 20(S)-hydroxylcholesterol.Structural biology of innate immunity.Identification of potential small molecule allosteric modulator sites on IL-1R1 ectodomain using accelerated conformational sampling method.Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 EctodomainSynapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus.TLR agonists: our best frenemy in cancer immunotherapyMolecular basis of NF-κB signalingStructure and function of chicken interleukin-1 beta mutants: uncoupling of receptor binding and in vivo biological activity.Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamilyMultifarious determinants of cytokine receptor signaling specificity.Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains.Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures.The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease.IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.Structural and Functional Attributes of the Interleukin-36 Receptor.Association of the Precursor of Interleukin-1β and Peritoneal Inflammation-Role in Pathogenesis of Endometriosis.The family of the interleukin-1 receptors.Function and regulation of IL-1α in inflammatory diseases and cancer.Homodimerization attenuates the anti-inflammatory activity of interleukin-37Development and Role in Therapy of Canakinumab in Adult-Onset Still's Disease
P2860
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P2860
Structure of the activating IL-1 receptor signaling complex
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structure of the activating IL-1 receptor signaling complex
@ast
Structure of the activating IL-1 receptor signaling complex
@en
Structure of the activating IL-1 receptor signaling complex
@nl
type
label
Structure of the activating IL-1 receptor signaling complex
@ast
Structure of the activating IL-1 receptor signaling complex
@en
Structure of the activating IL-1 receptor signaling complex
@nl
prefLabel
Structure of the activating IL-1 receptor signaling complex
@ast
Structure of the activating IL-1 receptor signaling complex
@en
Structure of the activating IL-1 receptor signaling complex
@nl
P2860
P3181
P356
P1476
Structure of the activating IL-1 receptor signaling complex
@en
P2093
J Fernando Bazan
K Christopher Garcia
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2260
P577
2012-03-18T00:00:00Z
P6179
1003588572