Structural Determinants of Integrin Binding to the Talin Rod - Wikidata - wikimedia - TriplyDB

Structural Determinants of Integrin Binding to the Talin Rod

Structural Determinants of Integrin Binding to the Talin Rod

http://www.wikidata.org/entity/Q27653581

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Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics The Structure of an Interdomain Complex That Regulates Talin Activity Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin The Rickettsia Surface Cell Antigen 4 Applies Mimicry to Bind to and Activate Vinculin RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1 Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering.Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.A microfluidic system with optical laser tweezers to study mechanotransduction and focal adhesion recruitment.Talins and kindlins: partners in integrin-mediated adhesion.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression The C terminus of talin links integrins to cell cycle progression.Absence of integrin αvβ3 enhances vascular leak in mice by inhibiting endothelial cortical actin formation Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activation The mechanical response of talin.Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.Structural and biophysical properties of the integrin-associated cytoskeletal protein talin.A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.Recent advances in the understanding of the molecular mechanisms regulating platelet integrin αIIbβ3 activation.Mechanisms of talin-dependent integrin signaling and crosstalk Role of vinculin in cellular mechanotransduction.Talin - the master of integrin adhesions.The NPIY motif in the integrin beta1 tail dictates the requirement for talin-1 in outside-in signaling Endothelial cell talin1 is essential for embryonic angiogenesis.Smurf1 zaps the talin head.Phosphatidylinositol 4,5-Bisphosphate Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates Its Autoinhibited Form.Vinculin regulates assembly of talin: β3 integrin complexes.

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P2860

Structural Determinants of Integrin Binding to the Talin Rod

http://www.wikidata.org/entity/Q27653581

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Structural Determinants of Integrin Binding to the Talin Rod

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Journal of Biological Chemistry

P1476

Structural determinants of integrin binding to the talin rod

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P2093

Andrey A Bobkov

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Anett Ritter

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Bipin Patel

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David R Critchley

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Domenico Fasci

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Igor L Barsukov

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J Günter Grossmann

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Jonas Emsley

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M Gordon Joyce

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Mark H Ginsberg

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P2860

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin

Structural determinants of integrin recognition by talin

Structural basis of integrin activation by talin

Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin

Determination of domain structure of proteins from X-ray solution scattering

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

The structure of the C-terminal actin-binding domain of talin

Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain

Coot: model-building tools for molecular graphics

Dali: a network tool for protein structure comparison

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8866-8876

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scholarly article

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4623438

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10.1074/JBC.M805937200

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13

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284

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Alexandre R Gingras

Wolfgang H. Ziegler

Benjamin T Goult

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2009-01-27T00:00:00Z

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19176533

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2659244

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