N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors
about
Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugsMetabolic functions of FABPs--mechanisms and therapeutic implicationsBinding modes of three inhibitors 8CA, F8A and I4A to A-FABP studied based on molecular dynamics simulationFatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases.Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4)Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity.Lipid chaperones and metabolic inflammation.An approach to cyclohepta[b]indoles through an allenamide (4 + 3) cycloaddition-Grignard cyclization-Chugaev elimination sequence.Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis.Rhodium- and platinum-catalyzed [4+3] cycloaddition with concomitant indole annulation: synthesis of cyclohepta[b]indoles.Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.Recent advances in transition-metal-catalyzed reactions of alkynes with isoxazoles.Fluorinated alcohol-mediated [4 + 3] cycloaddition reaction of indolyl alcohols with cyclopentadiene.Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis
P2860
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P2860
N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@ast
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@en
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@nl
type
label
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@ast
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@en
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@nl
prefLabel
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@ast
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@en
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@nl
P2093
P1476
N-Benzyl-indolo carboxylic aci ...... ng protein (A-FABP) inhibitors
@en
P2093
Carmen Medina
Fredrik Lehmann
Jonas Uppenberg
Kristin Hammer
Lena Rondahl
Saba Haile
Stefan Svensson
Tjeerd Barf
P304
P356
10.1016/J.BMCL.2009.01.084
P407
P577
2009-03-15T00:00:00Z