Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity.
about
Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetesDevelopment of a radioiodinated triazolopyrimidine probe for nuclear medical imaging of fatty acid binding protein 4All-Purpose Containers? Lipid-Binding Protein - Drug InteractionsFatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases.Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2.Biomarkers of insulin sensitivity and insulin resistance: Past, present and future.CRABP-II- and FABP5-independent responsiveness of human glioblastoma cells to all-trans retinoic acidTriglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress.Cardiomyocyte Overexpression of FABP4 Aggravates Pressure Overload-Induced Heart Hypertrophy.Fatty acid binding proteins 4 and 5 in overweight prepubertal boys: effect of nutritional counselling and supplementation with an encapsulated fruit and vegetable juice concentrateFatty acid binding protein-4 (FABP4) is a hypoxia inducible gene that sensitizes mice to liver ischemia/reperfusion injury.Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr ResidueIL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies.Lipid content in hepatic and gonadal adipose tissue parallel aortic cholesterol accumulation in mice fed diets with different omega-6 PUFA to EPA plus DHA ratios.Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?Regulation of adipocyte lipolysis.Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism.Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Lipid chaperones and metabolic inflammation.Hepatic Induction of Fatty Acid Binding Protein 4 Plays a Pathogenic Role in Sepsis in Mice.Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding Mode.Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cellsFABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue-derived hormone levels in mouse models mimicking constipation-predominant IBS.A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target.Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
P2860
Q27703246-5DD6A52E-BCA8-4DDF-BA54-CA31AF64514FQ28537831-F9594407-B65F-4904-A43E-FA59005083A6Q28546452-2DA367DC-84CE-45A2-B215-9BF5E34AC044Q35042217-1CAC0FC7-85D3-4A8B-A392-9903C38A751CQ35097086-4E7895D4-0F18-4865-8685-0342C7D39214Q35652813-2F50A4EE-3404-4B42-AD2D-3EAB58029D70Q35742427-37F6F402-1D9A-44C6-8F2D-7ED3CFF612F1Q35854702-C6E222C0-8199-4802-A782-44A3D5AF4C0DQ36050356-3954C5E8-BD24-4A48-84D6-D0FBB815DAD9Q36370695-75A46432-FE4B-4738-87B2-05C070D0D309Q36901475-166E5D57-DE49-4218-A406-F08A2BFD60F0Q37008862-063FF53F-DE57-434E-A37E-0BA60086C7DFQ37305013-B0CC70A6-D3D9-478D-9194-1AABC1AC80E3Q37733535-97113B0E-A78F-4976-B1B5-F66D1E59CD94Q38050907-89B6937F-2AC4-4337-B1D5-E0307D513DD3Q38215702-EE56FEF4-A86D-44E9-B407-497D47344F89Q38682493-F0848D3A-9DD6-4B7C-AFDB-A0FA8F72248EQ38816283-7A63C012-0DDD-4E2D-B592-5C4498C81074Q38908903-A3DE9CB7-05CD-44DC-ADAA-FAFCC5DE3632Q38916737-20E2F353-E9AC-47F2-B31C-F2FA24F4F897Q39731432-674EE68E-9C94-4BF0-90A6-41ED97A3D647Q41680356-DB3D681E-7DC7-47A4-AE65-1043C2563217Q47265903-4E817C6F-F87D-48C8-B58F-1690F00A5887Q47674218-CF6ED19F-1AD6-452A-8A4C-D9104C1C968FQ47806448-5EA3A7EB-2932-4127-944B-4B5CF8B19E46
P2860
Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Small-molecule inhibitors of F ...... ice with diet-induced obesity.
@en
type
label
Small-molecule inhibitors of F ...... ice with diet-induced obesity.
@en
prefLabel
Small-molecule inhibitors of F ...... ice with diet-induced obesity.
@en
P2093
P2860
P356
P1476
Small-molecule inhibitors of F ...... ice with diet-induced obesity.
@en
P2093
Alberto Rojas-Triana
Cheng-Chi Chuang
Cliff C Cheng
Gerald W Shipps
James Jackson
Johannes Voigt
Joseph A Hedrick
P2860
P304
P356
10.1194/JLR.M012757
P577
2011-02-04T00:00:00Z