Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions
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A perspective on the structure and receptor binding properties of immunoglobulin G FcDimeric Architecture of the Hendra Virus Attachment Glycoprotein: Evidence for a Conserved Mode of AssemblyChemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan BiosynthesisSelective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor InteractionsEngineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal AntibodiesCrystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Postfusion Architecture with Extensive GlycosylationImmunoglobulin G1 Fc Domain Motions: Implications for Fc EngineeringCrystal structure of deglycosylated human IgG4-FcStructural Characterization of Anti-Inflammatory Immunoglobulin G Fc ProteinsImmune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesDynamics of inter-heavy chain interactions in human immunoglobulin G (IgG) subclasses studied by kinetic Fab arm exchange.Influence of glycosylation pattern on the molecular properties of monoclonal antibodies.Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applicationsGlycosylation of therapeutic proteins: an effective strategy to optimize efficacyTiming of galectin-1 exposure differentially modulates Nipah virus entry and syncytium formation in endothelial cells.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.The Structural Role of Antibody N-Glycosylation in Receptor InteractionsChemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic SequonFunction and 3D structure of the N-glycans on glycoproteins.Glycosylation: impact, control and improvement during therapeutic protein production.Structural transitions of the conserved and metastable hantaviral glycoprotein envelope.Binding structures and energies of the human neonatal Fc receptor with human Fc and its mutants by molecular modeling and dynamics simulations.Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120.Global N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry.Optimization of protein-protein docking for predicting Fc-protein interactions.Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity.Separation of nonfucosylated antibodies with immobilized FcγRIII receptors.Structural characterization of the Man5 glycoform of human IgG3 Fc.Structural analysis of glycoproteins: building N-linked glycans with Coot.
P2860
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P2860
Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Carbohydrate and domain archit ...... ng enhanced effector functions
@ast
Carbohydrate and domain archit ...... ng enhanced effector functions
@en
Carbohydrate and domain archit ...... ng enhanced effector functions
@nl
type
label
Carbohydrate and domain archit ...... ng enhanced effector functions
@ast
Carbohydrate and domain archit ...... ng enhanced effector functions
@en
Carbohydrate and domain archit ...... ng enhanced effector functions
@nl
prefLabel
Carbohydrate and domain archit ...... ng enhanced effector functions
@ast
Carbohydrate and domain archit ...... ng enhanced effector functions
@en
Carbohydrate and domain archit ...... ng enhanced effector functions
@nl
P2093
P50
P3181
P1476
Carbohydrate and domain archit ...... ng enhanced effector functions
@en
P2093
A Radu Aricescu
David J Harvey
E Yvonne Jones
P304
P3181
P356
10.1016/J.JMB.2009.02.033
P407
P577
2009-04-17T00:00:00Z