Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
about
Glycoproteomic and glycomic databasesImmunogenicity of Biotherapeutics: Causes and Association with Posttranslational ModificationsSite-specific functionalization of proteins and their applications to therapeutic antibodiesDaedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectorsGlycan analysis of therapeutic glycoproteinsA new recombinant factor VIII: from genetics to clinical use.Moisture-induced solid state instabilities in alpha-chymotrypsin and their reduction through chemical glycosylation.Sialic acid linkage differentiation of glycopeptides using capillary electrophoresis - electrospray ionization - mass spectrometryGlycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides.His-FLAG Tag as a Fusion Partner of Glycosylated Human Interferon-Gamma and Its Mutant: Gain or Loss?A new insect cell glycoengineering approach provides baculovirus-inducible glycogene expression and increases human-type glycosylation efficiency.Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contextsIntegrating bioinformatics tools to handle glycosylationPlant glyco-biotechnology on the way to synthetic biologyMolecular characterization and functional activity of an IL-15 antagonist MutIL-15/Fc human fusion protein.Tandem mass spectra of glycan substructures enable the multistage mass spectrometric identification of determinants on oligosaccharides.Exploring the N-glycosylation pathway in Chlamydomonas reinhardtii unravels novel complex structures.Chemically glycosylation improves the stability of an amperometric horseradish peroxidase biosensorFunctional relevance of protein glycosylation to the pro-inflammatory effects of extracellular matrix metalloproteinase inducer (EMMPRIN) on monocytes/macrophagesSite-specific protein modifications through pyrroline-carboxy-lysine residuesDirect site-specific glycoform identification and quantitative comparison of glycoprotein therapeutics: imiglucerase and velaglucerase alfaConvergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism.A Microarray-Matrix-assisted Laser Desorption/Ionization-Mass Spectrometry Approach for Site-specific Protein N-glycosylation Analysis, as Demonstrated for Human Serum Immunoglobulin M (IgM).The major secreted protein Msp1/p75 is O-glycosylated in Lactobacillus rhamnosus GG.A Quantitative Microtiter Assay for Sialylated Glycoform Analyses Using Lectin Complexes.Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges.Site-selective glycosylation of hemoglobin with variable molecular weight oligosaccharides: potential alternative to PEGylation.In silico design and analysis of a new hyperglycosylated analog of erythropoietin to improve drug efficacy.Multivalent Conjugates of Sonic Hedgehog Accelerate Diabetic Wound Healing.Fully Synthetic Granulocyte Colony-Stimulating Factor Enabled by Isonitrile-Mediated Coupling of Large, Side-Chain-Unprotected PeptidesTargeted glycoengineering extends the protein N-glycosylation pathway in the silkworm silk glandProperties of genes essential for mouse development.Impact of a human CMP-sialic acid transporter on recombinant glycoprotein sialylation in glycoengineered insect cells.N-glycosylation of enhanced aromatic sequons to increase glycoprotein stabilityCharacterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).The use of lectin microarray for assessing glycosylation of therapeutic proteins.Effects of Rho1, a small GTPase on the production of recombinant glycoproteins in Saccharomyces cerevisiaeProtein engineering for cardiovascular therapeutics: untapped potential for cardiac repair.Delivery of chemically glycosylated cytochrome c immobilized in mesoporous silica nanoparticles induces apoptosis in HeLa cancer cells.Chemoenzymatic bio-orthogonal chemistry for site-specific double modification of recombinant thrombomodulin
P2860
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P2860
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@ast
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@en
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.
@nl
type
label
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@ast
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@en
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.
@nl
prefLabel
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@ast
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@en
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.
@nl
P2860
P1433
P1476
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy
@en
P2093
Kai Griebenow
Ricardo J Solá
P2860
P356
10.2165/11530550-000000000-00000
P577
2010-02-01T00:00:00Z
P5875
P6179
1025543499