Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
about
tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerasesCrystal structures of the catalytic domain of human soluble guanylate cyclaseCrystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonateCardiac cAMP: production, hydrolysis, modulation and detectionTrinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca 2+ -ATPase in the absence of Ca 2+Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosaStructure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing ComplexStructural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes-implications for cyclase catalysis and evolutionSubstrate specificity determinants of class III nucleotidyl cyclasesLuciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readoutsEmpirical valence bond simulations of the chemical mechanism of ATP to cAMP conversion by anthrax edema factor.Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.Regulation by Ca2+-signaling pathways of adenylyl cyclases.Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compoundsThe chemistry and biology of soluble guanylate cyclase stimulators and activators.Adenylate cyclase-centred microdomains.Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Impact of divalent metal ions on regulation of adenylyl cyclase isoforms by forskolin analogs.The effect of alcohol on recombinant proteins derived from mammalian adenylyl cyclaseElevated carbon dioxide blunts mammalian cAMP signaling dependent on inositol 1,4,5-triphosphate receptor-mediated Ca2+ release.Exploring the inhibition mechanism of adenylyl cyclase type 5 by n-terminal myristoylated Gαi1Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody.A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of arms.Discovery of potent inhibitors of human β-tryptase from pre-equilibrated dynamic combinatorial libraries.Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6.Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production.Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease.
P2860
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P2860
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@ast
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@en
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@nl
type
label
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@ast
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@en
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@nl
prefLabel
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@ast
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@en
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@nl
P2093
P2860
P356
P1433
P1476
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †
@en
P2093
Dermot M F Cooper
Nanako Masada
Stephen R Sprang
P2860
P304
P356
10.1021/BI802122K
P407
P577
2009-04-21T00:00:00Z