X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design
about
Histidine hydrogen-deuterium exchange mass spectrometry for probing the microenvironment of histidine residues in dihydrofolate reductaseAn innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymesNew developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracisUtility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.Classification of ligand molecules in PDB with graph match-based structural superposition.Structural analysis of dihydrofolate reductases enables rationalization of antifolate binding affinities and suggests repurposing possibilities.Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.Acceleration of Binding Site Comparisons by Graph Partitioning.
P2860
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P2860
X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
X-ray structure of the ternary ...... for dual-site inhibitor design
@ast
X-ray structure of the ternary ...... for dual-site inhibitor design
@en
X-ray structure of the ternary ...... for dual-site inhibitor design
@nl
type
label
X-ray structure of the ternary ...... for dual-site inhibitor design
@ast
X-ray structure of the ternary ...... for dual-site inhibitor design
@en
X-ray structure of the ternary ...... for dual-site inhibitor design
@nl
prefLabel
X-ray structure of the ternary ...... for dual-site inhibitor design
@ast
X-ray structure of the ternary ...... for dual-site inhibitor design
@en
X-ray structure of the ternary ...... for dual-site inhibitor design
@nl
P2093
P2860
P1476
X-ray structure of the ternary ...... for dual-site inhibitor design
@en
P2093
Brad C Bennett
Chris G Dealwis
Md Faiz Ahmad
P2860
P304
P356
10.1016/J.JSB.2009.01.001
P577
2009-05-01T00:00:00Z