Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis - Wikidata - wikimedia - TriplyDB

Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis

Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis

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Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex.

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P2860

Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis

http://www.wikidata.org/entity/Q34781493

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2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

@ast

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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type

label

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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prefLabel

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

@ast

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

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J.BMC.2014.11.009

P1433

Bioorganic & Medicinal Chemistry

P1476

Modified 2,4-diaminopyrimidine ...... lds against Bacillus anthracis

@en

P2093

Baskar Nammalwar

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Christina R Bourne

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Esther W Barrow

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K Darrell Berlin

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N Prasad Muddala

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Nancy Wakeham

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Philip C Bourne

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Richard A Bunce

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William W Barrow

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P2860

Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity

Crystal Structure of Bacillus anthracis Dihydrofolate Reductase with the Dihydrophthalazine-Based Trimethoprim Derivative RAB1 Provides a Structural Explanation of Potency and Selectivity

X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines

Inhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidines

Antibiotic resistance is ancient

Structure–activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase

Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding mode

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

P304

203-211

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scholarly article

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10.1016/J.BMC.2014.11.009

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1

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23

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2014-11-11T00:00:00Z

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25435253

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4278362

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