Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP
about
Structural Analysis of the 14-3-3ζ/Chibby Interaction Involved in Wnt/β-Catenin SignalingA protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal componentsAn allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1Structural basis for the nuclear export activity of Importin13Structural basis for cooperative RNA binding and export complex assembly by HIV RevA structurally plastic ribonucleoprotein complex mediates post-transcriptional gene regulation in HIV-1Capturing Biological Activity in Natural Product Fragments by Chemical SynthesisStructural Basis of Targeting the Exportin CRM1 in CancerRan-dependent nuclear export mediators: a structural perspectiveNuclear export of proteins and drug resistance in cancerThe interaction of CRM1 and the nuclear pore protein TprStructures of the tRNA export factor in the nuclear and cytosolic statesA high-resolution structure of the pre-microRNA nuclear export machineryConformational selection in the recognition of the snurportin importin beta binding domain by importin betaNES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding DomainStructural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cellsSelective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemiaStructural basis for cooperativity of CRM1 export complex formationNuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1Structure and Topology of the Huntingtin 1–17 Membrane Anchor by a Combined Solution and Solid-State NMR ApproachNext-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignanciesCex1p facilitates Rna1p-mediated dissociation of the Los1p-tRNA-Gsp1p-GTP export complex.A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexesThe export receptor Crm1 forms a dimer to promote nuclear export of HIV RNAGenomic and molecular characterization of esophageal squamous cell carcinomaEvolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replicationThe nuclear pore complex and nuclear transportProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical spaceA bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export.Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropismCombining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex.The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complexAtomic basis of CRM1-cargo recognition, release and inhibitionThe importin β binding domain as a master regulator of nucleocytoplasmic transportKPT-330 inhibitor of XPO1-mediated nuclear export has anti-proliferative activity in hepatocellular carcinoma.Recognition of nuclear targeting signals by Karyopherin-β proteins.Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents
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P2860
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@ast
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@en
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@nl
type
label
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@ast
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@en
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@nl
prefLabel
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@ast
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@en
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@nl
P2860
P50
P3181
P356
P1433
P1476
Crystal structure of the nucle ...... ex with Snurportin1 and RanGTP
@en
P2860
P304
P3181
P356
10.1126/SCIENCE.1173388
P407
P577
2009-05-22T00:00:00Z