Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS
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Dysregulated metabolism contributes to oncogenesisMechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinismA novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysisGreen Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation SiteMultiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological ImplicationsBinding leverage as a molecular basis for allosteric regulationMolecular mechanisms of protein induced hyperinsulinaemic hypoglycaemia.Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry)Antibacterial mechanisms identified through structural systems pharmacology.Therapeutic targeting of cancer cell metabolism.A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication.Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator SiteSensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphataseIdentification of Multiple Cryptococcal Fungicidal Drug Targets by Combined Gene Dosing and Drug Affinity Responsive Target Stability Screening.In silico prediction of antimalarial drug target candidates.Glutamine and glutaminolysis are required for efficient replication of infectious spleen and kidney necrosis virus in Chinese perch brain cells.The structure and allosteric regulation of glutamate dehydrogenase.Glutamate dehydrogenase: structure, allosteric regulation, and role in insulin homeostasis.Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase.Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells.Purification, crystallization and preliminary X-ray diffraction analysis of NADP-dependent glutamate dehydrogenase from Aspergillus niger.Neuronal Glud1 (glutamate dehydrogenase 1) over-expressing mice: increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression.Affordable uniform isotope labeling with (2)H, (13)C and (15)N in insect cells.Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes.Structure, function, and regulation of enzymes involved in amino acid metabolism of bacteria and archaea.Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons.Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point.Nutrient sensing in pancreatic islets: lessons from congenital hyperinsulinism and monogenic diabetes.Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia
P2860
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P2860
Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@ast
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@en
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@nl
type
label
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@ast
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@en
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@nl
prefLabel
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@ast
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@en
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@nl
P2093
P2860
P3181
P356
P1476
Novel Inhibitors Complexed wit ...... BY CONTROL OF PROTEIN DYNAMICS
@en
P2093
Christopher J Smith
Matthew T Walker
P2860
P304
22988-3000
P3181
P356
10.1074/JBC.M109.020222
P407
P577
2009-08-21T00:00:00Z