Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
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Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygenScreening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)Prolyl 4-hydroxylaseTargeting Protein-Protein Interactions in the HIF SystemHypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?Thermal unfolding pathway of PHD2 catalytic domain in three different PHD2 species: computational approachesCrystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complexSelective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic ApproachesThe oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylasesAb Initio Structural Modeling of and Experimental Validation for Chlamydia trachomatis Protein CT296 Reveal Structural Similarity to Fe(II) 2-Oxoglutarate-Dependent EnzymesCrystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMDInvestigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygenStructural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription.Lessons from making the Structural Classification of Proteins (SCOP) and their implications for protein structure modellingInhibition of 2-oxoglutarate dependent oxygenasesPrediction and analysis of protein hydroxyproline and hydroxylysinePotent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine BrainThe role of PHD2 mutations in the pathogenesis of erythrocytosis.The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerensSubstrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change.The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolismGene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations.Sequence Analysis and Phylogenetic Studies of Hypoxia-Inducible Factor-1αErythrocytosis associated with a novel missense mutation in the HIF2A gene.A photoreactive small-molecule probe for 2-oxoglutarate oxygenases.Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibilityAnalysis of hypoxia-inducible factor alpha polyploidization reveals adaptation to Tibetan Plateau in the evolution of schizothoracine fishHuman oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylationDynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylasesProtein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases.Conformational changes associated with post-translational modifications of Pro(143) in Skp1 of Dictyostelium--a dipeptide model system.Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.Vitamin C is dispensable for oxygen sensing in vivoThe ubiquitin E3 ligase SCF-FBXO24 recognizes deacetylated nucleoside diphosphate kinase A to enhance its degradation.Hypoxia regulates glutamate receptor trafficking through an HIF-independent mechanismKinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8.Two new mutations in the HIF2A gene associated with erythrocytosis.PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.
P2860
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P2860
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@ast
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@en
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@nl
type
label
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@ast
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@en
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@nl
prefLabel
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@ast
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@en
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@nl
P50
P3181
P1433
P1476
Structural basis for binding o ...... en-sensing prolyl hydroxylases
@en
P2093
Kirsty S Hewitson
P304
P3181
P356
10.1016/J.STR.2009.06.002
P407
P50
P577
2009-07-01T00:00:00Z