Structure and Mechanism of a Na+-Independent Amino Acid Transporter
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Insights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDATHow LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transportersA conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic ResiduesModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueMolecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1Design, function and structure of a monomeric ClC transporterThe mechanism of sodium and substrate release from the binding pocket of vSGLTSubstrate specificity and ion coupling in the Na+/betaine symporter BetPMolecular basis of substrate-induced permeation by an amino acid antiporterCrystal structure of the maltose transporter in a pretranslocation intermediate stateStructural Analysis of a Protective Epitope of the Francisella tularensis O -PolysaccharideX-ray structures of LeuT in substrate-free outward-open and apo inward-open statesStructure and mechanism of a glutamate-GABA antiporterArginine oscillation explains Na+ independence in the substrate/product antiporter CaiTMolecular mechanism of ligand recognition by membrane transport protein, Mhp1Saccharomyces cerevisiae-based platform for rapid production and evaluation of eukaryotic nutrient transporters and transceptors for biochemical studies and crystallographyMolecular and evolutionary insights into the structural organization of cation chloride cotransportersMutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.Structures of membrane proteins.Overcoming barriers to membrane protein structure determination.A gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporterA single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters.Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters.Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.Conformational dynamics of ligand-dependent alternating access in LeuT.Molecular modeling and ligand docking for solute carrier (SLC) transportersComparison of human solute carriersSystematic mutational analysis of the intracellular regions of yeast Gap1 permease.High-efficiency screening of monoclonal antibodies for membrane protein crystallographyDynamic superresolution imaging of endogenous proteins on living cells at ultra-high densityUnbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters.Single-molecule dynamics of gating in a neurotransmitter transporter homologueThe transport mechanism of the human sodium/myo-inositol transporter 2 (SMIT2/SGLT6), a member of the LeuT structural family.System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.Conserved tyrosine in the first transmembrane segment of solute:sodium symporters is involved in Na+-coupled substrate co-transport.
P2860
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P2860
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@ast
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@en
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@nl
type
label
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@ast
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@en
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@nl
prefLabel
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@ast
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@en
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
@en
P2093
April Goehring
Aruna Shankaranarayanan
Paul L Shaffer
P2860
P304
P3181
P356
10.1126/SCIENCE.1176088
P407
P50
P577
2009-08-21T00:00:00Z