Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38 - Wikidata - wikimedia - TriplyDB

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

http://www.wikidata.org/entity/Q27656752

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Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2 Compartmentation of NAD+-dependent signalling.Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling.Roles of cADPR and NAADP in pancreatic cells.Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization.Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38.A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle.Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.CD38 deficiency suppresses adipogenesis and lipogenesis in adipose tissues through activating Sirt1/PPARγ signaling pathway.Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid "L-cyclic inosine 5'-diphosphate ribose".TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes.The Emergence of the Nicotinamide Riboside Kinases in the regulation of NAD+ Metabolism.

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Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

http://www.wikidata.org/entity/Q27656752

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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type

label

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

@en

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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prefLabel

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

@ast

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

@en

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

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Hon Cheung Lee

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Irina A Kriksunov

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Norman Oppenheimer

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Quan Hao

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Richard Graeff

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P2860

Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Improved methods for building protein models in electron density maps and the location of errors in these models

Processing of X-ray diffraction data collected in oscillation mode

Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase

Crystal structure of Aplysia ADP ribosyl cyclase, a homologue of the bifunctional ectozyme CD38

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

ARP/wARP and automatic interpretation of protein electron density maps

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

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