An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9
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Human Nek7-interactor RGS2 is required for mitotic spindle organization.Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural CharacterizationA Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases: DISCOVERY OF ATP-INDEPENDENT INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTORCrystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiationMolecular Features of Product Release for the PKA Catalytic CycleEfficient genetic encoding of phosphoserine and its nonhydrolyzable analogA new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinaseMolecular mechanisms of human IRE1 activation through dimerization and ligand bindingLimitations of Ab initio predictions of peptide binding to MHC class II molecules"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinasesHuman Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin.NEK9-dependent proliferation of cancer cells lacking functional p53Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.Microarray characterization of gene expression changes in blood during acute ethanol exposureC. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting.Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase.αC helix as a switch in the conformational transition of Src/CDK-like kinase domains.Breaking the ties that bind: new advances in centrosome biology.Cell cycle regulation by the NEK family of protein kinases.On the molecular mechanisms of mitotic kinase activation.The structural mechanisms that underpin mitotic kinase activation.Structure, function, and evolution of plant NIMA-related kinases: implication for phosphorylation-dependent microtubule regulation.Revealing protein networks and gene-drug connectivity in cancer from direct information.Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1.Structure-functional prediction and analysis of cancer mutation effects in protein kinases.Nek family of kinases in cell cycle, checkpoint control and cancer.NEK7 is an essential mediator of NLRP3 activation downstream of potassium effluxDYNLL/LC8 protein controls signal transduction through the Nek9/Nek6 signaling module by regulating Nek6 binding to Nek9.Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.Activation of NIMA Kinases NEK9, NEK6, NEK7Mitotic Regulation by NEK Kinase Networks.A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase.NEK9 phosphorylates NEK6/NEK7NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana.A kinetic test characterizes kinase intramolecular and intermolecular autophosphorylation mechanisms.NIMA-related kinase NEK6 affects plant growth and stress response in Arabidopsis.Gatekeeper tyrosine phosphorylation is autoinhibitory for Symbiosis Receptor Kinase.
P2860
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P2860
An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@ast
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en-gb
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@nl
type
label
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@ast
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en-gb
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@nl
prefLabel
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@ast
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en-gb
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@nl
P2093
P2860
P50
P3181
P1433
P1476
An Autoinhibitory Tyrosine Mot ...... leased through Binding of Nek9
@en
P2093
Corine Mas-Droux
Jack Cheung
Joelle M Y Blot
Swen Hoelder
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2009.09.038
P577
2009-11-25T00:00:00Z