about
Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domainMitotic regulation by NIMA-related kinasesAn Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domainHistone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cellsHsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.EML proteins in microtubule regulation and human disease.Cell cycle regulation by the NEK family of protein kinases.The Nek6 and Nek7 protein kinases are required for robust mitotic spindle formation and cytokinesis.Novel insights into the mechanisms of mitotic spindle assembly by NEK kinasesHsp70 proteins in mitosis and disease.Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells.Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
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researcher
@en-gb
հետազոտող
@hy
name
Laura O'Regan
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Laura O'Regan
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Laura O'Regan
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Laura O'Regan
@es
Laura O'Regan
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Laura O'Regan
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type
label
Laura O'Regan
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Laura O'Regan
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Laura O'Regan
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Laura O'Regan
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Laura O'Regan
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Laura O'Regan
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prefLabel
Laura O'Regan
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Laura O'Regan
@en
Laura O'Regan
@en-gb
Laura O'Regan
@es
Laura O'Regan
@nl
Laura O'Regan
@sl
P106
P21
P31
P496
0000-0002-6101-6300