about
Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylationThe Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of ProteinsAdding a Lysine Mimic in the Design of Potent Inhibitors of Histone Lysine MethyltransferasesStructural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA bindingStructural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signalingThe CW domain, a new histone recognition module in chromatin proteinsChemogenetic analysis of human protein methyltransferasesSolution Structure of MSL2 CXC Domain Reveals an Unusual Zn3Cys9 Cluster and Similarity to Pre-SET Domains of Histone Lysine MethyltransferasesMPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9aDefining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylationStructure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic MutationsStructural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET DomainSRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylationCrystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2Diverse involvement of EZH2 in cancer epigeneticsUbiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase ActivityLong term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylationDNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cellsTheoretical insights into catalytic mechanism of protein arginine methyltransferase 1Open access target validation is a more efficient way to accelerate drug discoveryBhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assemblyA histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreadingMutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesAccessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresisFluorescence-based methods for screening writers and readers of histone methyl marks.Efficient hit-finding approaches for histone methyltransferases: the key parameters.Mutations in EZH2 cause Weaver syndrome.Mechanism of retinoic acid-induced transcription: histone code, DNA oxidation and formation of chromatin loops.Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compoundsInner workings and regulatory inputs that control Polycomb repressive complex 2QM/MM MD and free energy simulations of G9a-like protein (GLP) and its mutants: understanding the factors that determine the product specificityEZH2: biology, disease, and structure-based drug discoveryCoordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas.Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small moleculesIn vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.A mutation in the SUV39H2 gene in Labrador Retrievers with hereditary nasal parakeratosis (HNPK) provides insights into the epigenetics of keratinocyte differentiationAlternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions.Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural Biology of Human H3K9 Methyltransferases
@ast
Structural Biology of Human H3K9 Methyltransferases
@en
Structural Biology of Human H3K9 Methyltransferases
@nl
type
label
Structural Biology of Human H3K9 Methyltransferases
@ast
Structural Biology of Human H3K9 Methyltransferases
@en
Structural Biology of Human H3K9 Methyltransferases
@nl
prefLabel
Structural Biology of Human H3K9 Methyltransferases
@ast
Structural Biology of Human H3K9 Methyltransferases
@en
Structural Biology of Human H3K9 Methyltransferases
@nl
P2093
P2860
P50
P3181
P1433
P1476
Structural Biology of Human H3K9 Methyltransferases
@en
P2093
Alexander N Plotnikov
Jinrong Min
Valérie Campagna-Slater
Vladimir V Lunin
P2860
P3181
P356
10.1371/JOURNAL.PONE.0008570
P407
P50
P577
2010-01-11T00:00:00Z