Discovery of 4-Amino-1-(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

Discovery of 4-Amino-1-(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

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http://www.wikidata.org/entity/Q27659777
Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold MorphingAkt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plantsPI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.Glaucocalyxin A, a negative Akt regulator, specifically induces apoptosis in human brain glioblastoma U87MG cells.Preclinical pharmacology, antitumor activity, and development of pharmacodynamic markers for the novel, potent AKT inhibitor CCT128930.A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site.Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview.Pyrrolo[2,3-d]pyrimidine synthesis through activation of N-benzyl groups by distal amides.ProSelection: A Novel Algorithm to Select Proper Protein Structure Subsets for in Silico Target Identification and Drug Discovery Research.
P2860

Discovery of 4-Amino-1-(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)

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http://www.wikidata.org/entity/Q27659777
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@ast
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@en
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
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type
label
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@ast
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@en
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@nl
prefLabel
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@ast
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@en
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P3181
P356
P1433
P1476
Discovery of 4-Amino-1-(7 H -p ...... tors of Protein Kinase B (Akt)
@en
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P921
P932