Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation
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Regulation of small GTPases by GEFs, GAPs, and GDIsRegulating the large Sec7 ARF guanine nucleotide exchange factors: the when, where and how of activationStructure of the Rho-specific guanine nucleotide-exchange factor XplnStructural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica PathogenesisIntegrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2Crystal structure of mouse RhoA:GTPγS complex in a centered latticeStructural Insights into the Activation of the RhoA GTPase by the Lymphoid Blast Crisis (Lbc) OncoproteinCollybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission.RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEFCalmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insightsPlasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cellsSignalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis.Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domainSecondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEFPH motifs in PAR1&2 endow breast cancer growth.Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins.Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7.Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms.RhoGEFs in cell motility: novel links between Rgnef and focal adhesion kinase.Serum brain-type creatine kinase increases in children with osteogenesis imperfecta during neridronate treatment.Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns.A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy.Modeling of protein complexes in CAPRI Round 37 using template-based approach combined with model selection.Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
P2860
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P2860
Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@ast
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@en
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@nl
type
label
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@ast
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@en
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@nl
prefLabel
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@ast
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@en
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@nl
P2093
P2860
P356
P1476
Activated RhoA Binds to the Pl ...... ential Site for Autoregulation
@en
P2093
Celestine Thomas
Frank Medina
Paul C Sternweis
Stephen R Sprang
P2860
P304
P356
10.1074/JBC.M110.122549
P407
P577
2010-07-02T00:00:00Z