The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery

The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery

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http://www.wikidata.org/entity/Q27663417
`In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinaseStructures of pyruvate kinases display evolutionarily divergent allosteric strategiesStabilization of the predominant disease-causing aldolase variant (A149P) with zwitterionic osmolytesImpairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination.What Mutagenesis Can and Cannot Reveal About Allostery.Benchmarking predictions of allostery in liver pyruvate kinase in CAGI4.Exploring the limits of the usefulness of mutagenesis in studies of allosteric mechanisms.Identification of regions of rabbit muscle pyruvate kinase important for allosteric regulation by phenylalanine, detected by H/D exchange mass spectrometry.Effector analogues detect varied allosteric roles for conserved protein-effector interactions in pyruvate kinase isozymes.An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.
P2860

The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery

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http://www.wikidata.org/entity/Q27663417
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2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
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2010年论文
@wuu
name
The pyruvate kinase model syst ...... tional equilibria in allostery
@ast
The pyruvate kinase model syst ...... tional equilibria in allostery
@en
The pyruvate kinase model syst ...... tional equilibria in allostery
@nl
type
label
The pyruvate kinase model syst ...... tional equilibria in allostery
@ast
The pyruvate kinase model syst ...... tional equilibria in allostery
@en
The pyruvate kinase model syst ...... tional equilibria in allostery
@nl
prefLabel
The pyruvate kinase model syst ...... tional equilibria in allostery
@ast
The pyruvate kinase model syst ...... tional equilibria in allostery
@en
The pyruvate kinase model syst ...... tional equilibria in allostery
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
The pyruvate kinase model syst ...... tional equilibria in allostery
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932